Minnelide

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DB17309InvestigationalSmall molecule

Minnelide: Overview.

Formula / weight: C₂₁H₂₅Na₂O₁₀P · 514.374 g/mol (avg)
Also known as: 14-o-phosphonooxymethyltriptolide disodium salt · Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium salt (1:2), (3bs,4as,5ar,6r,6as,7as,7bs,8as,8bs)-

Resolves to

Compound

UNII1CIV2UMO40CAS1254702-87-8ChEMBLCHEMBL3740500

Structure

InChIKeyZHBJMVNZRZUQEP-KIKMAQITSA-LSMILES[Na+].[Na+].[H][C@@]12C[C@@H]3O[C@@]33[C@H](OCOP([O-])([O-])=O)[C@]4(O[C@H]4[C@@H]4O[C@]34[C@@]1(C)CCC1=C2COC1=O)C(C)C

Targets

P0DMV9HSPA1BP0DMV8HSPA1A

What you can answer from here — as of April 23, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

9Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Minnelide, and which of those have an active Phase 3 trial?

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