Heat shock 70 kDa protein 1B

BE0012549ProteinHumansHSPA1B

Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation... It is acted on by 4 drugs in DrugBank.

Gene name
HSPA1B
UniProtKB entry
P0DMV9Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
641 residues · 70,052 Da
Also known as
Heat shock 70 kDa protein 2 · Heat shock protein family A member 1B · HSP70-2 · HSP70.2 · HSP72

Resolves to

Protein
UniProtP0DMV9UniProt nameHS71B_HUMAN
Gene
HGNCHGNC:5233NCBI Gene3304GeneCardsHSPA1B
Pharmacology
KEGGhsa:3304
Structure
PDB4J8FPDB6FDTPDB7F4X
Drugs

What you can answer from here — as of September 03, 2024

4DrugsApproved to experimental, with action, bond type and pharmacological action
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56GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Heat shock 70 kDa protein 1B, and which indications are they being tested in?

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