Dotamtate Pb-212

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DB17312InvestigationalSmall molecule

Dotamtate Pb-212: Overview.

Mechanism: Pharmacologically active on Somatostatin receptor
Curator reviewed
Formula / weight: C₆₅H₉₁N₁₇O₁₆PbS₂ · 1642.66 g/mol (avg)
Also known as: 212Pb-dotamtate · Alphamedix · Dotamtate lead Pb-212 · Lead-212 dotamtate

Resolves to

Compound

UNIIE9N7QV53AK

Structure

InChIKeyXWRQOPLCTVHUPG-DGSPUKEMSA-LSMILES

[212Pb++].[H][C@](C)(O)[C@]([H])(N=C(O)[C@]1([H])CSSC[C@]([H])(N=C(O)[C@@]([H])(CC2=CC=CC=C2)N=C(O)CN2CCN(CC(O)=N)CCN(CC([O-])=N)CCN(CC(O)=N)CC2)C(O)=N[C@@]([H])(CC2=CC=C([O-])C=C2)C(O)=N[C@]([H])(CC2=CNC3=CC=CC=C23)C(O)=N[C@@]([H])(CCCCN)C(O)=N[C@]([H])(C(O)=N1)[C@@]([H])(C)O)C(O)=O

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which companies are running trials of Dotamtate Pb-212, in which indications and phases, and which of those programs are still active?

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