DB17449ApprovedInvestigationalProtein Based Therapies
Anacaulase is a mix of proteolytic enzymes indicated for eschar removal in adults with deep partial thickness and/or full-thickness thermal burns. Anacaulase (anacaulase-bcdb) is a mixture of proteolytic enzymes extracted from the stems of pineapple plants (Ananas comosus [L.] Merr.).
- Mechanism
- Curator reviewed · 1 reference
The mechanism of action of anacaulase is not clear. The mixture of enzymes in anacaulase dissolves burn wound eschar; however, the components responsible for this effect have not been identified.
- Primary indication
- Anacaulase is indicated for eschar removal in adults and pediatric patients with deep partial thickness and/or full-thickness thermal burns.Curator reviewed · 2 structured indications
- Formula / weight
- 23000.0 Da (average weight of proteolitic enzymes in mix)
- First approval
- United States, 2022
- Also known as
- Anacaulase-bcdb
- Brand names
Resolves to
Compound
Clinical / RWD
Targets
What you can answer from here — as of February 24, 2026
2Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Anacaulase, and which of those have an active Phase 3 trial?
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