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Udonitrectag

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Data Packages
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Identification

Generic Name
Udonitrectag
DrugBank Accession Number
DB18013
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 353.374
Monoisotopic: 353.126322716
Chemical Formula
C20H19NO5
Synonyms
  • (1s,4r,5r,7s)-2-oxo-3,4-bis(phenylmethyl)-6,8-dioxa-3-azabicyclo(3.2.1)octane-7-carboxylate
  • (1s,4r,5r,7s)-3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid
  • 3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid, (1s,4r,5r,7s)-
  • 6,8-dioxa-3-azabicyclo(3.2.1)octane-7-carboxylic acid, 2-oxo-3,4-bis(phenylmethyl)-, (1s,4r,5r,7s)-
  • Rec-0559 (nerve growth factor mimetic)
External IDs
  • REC 0559
  • REC-0559
  • REC0559
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Udonitrectag L-lysine6C16I5288U1458063-51-8Not applicable

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
2GOW9TT6AD
CAS number
1458063-04-1
InChI Key
SEKGLVUAECPQQM-NHAYFPRASA-N
InChI
InChI=1S/C20H19NO5/c22-18-16-17(19(23)24)26-20(25-16)15(11-13-7-3-1-4-8-13)21(18)12-14-9-5-2-6-10-14/h1-10,15-17,20H,11-12H2,(H,23,24)/t15-,16+,17-,20+/m0/s1
IUPAC Name
(1S,4R,5R,7S)-3,4-dibenzyl-2-oxo-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-carboxylic acid
SMILES
OC(=O)[C@H]1O[C@H]2O[C@@H]1C(=O)N(CC1=CC=CC=C1)[C@@H]2CC1=CC=CC=C1

References

General References
Not Available
ChemSpider
81367614
ChEMBL
CHEMBL4594439

Clinical Trials

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2CompletedTreatmentNeurotrophic Keratopathy1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP2.45Chemaxon
pKa (Strongest Acidic)3.79Chemaxon
pKa (Strongest Basic)3.01Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count5Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area76.07 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity91.78 m3·mol-1Chemaxon
Polarizability35.69 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at September 06, 2023 21:10 / Updated at September 28, 2023 05:47