Zilurgisertib

DB18152InvestigationalSmall molecule

Zilurgisertib: Overview.

Mechanism: Pharmacologically active on Activin receptor type-1
Curator reviewed
Formula / weight: C₃₀H₃₈N₄O₃ · 502.659 g/mol (avg)
Code names: INCB-000928 · NBU-928 free base

Resolves to

Compound

Structure

InChIKeyKPRPFTOLWQQUAV-OCVAFRRMSA-NSMILESNC1=NC=C(C=C1C(=O)NC12CCC(O)(CC1)CC2)C1=CC=C(C=C1)[C@@]12C[C@@H]1CN(C2)C1CCOCC1

Targets

What you can answer from here — as of September 29, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

1Structured indicationCondition, population, route and combination as fields, not prose

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Zilurgisertib, and which of those have an active Phase 3 trial?

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