Zilurgisertib

DB18152InvestigationalSmall molecule

Zilurgisertib: Overview.

Mechanism: Pharmacologically active on Activin receptor type-1
Curator reviewed
Formula / weight: C₃₀H₃₈N₄O₃ · 502.659 g/mol (avg)
Code names: INCB-000928 · NBU-928 free base

Resolves to

Compound

Structure

InChIKeyKPRPFTOLWQQUAV-OCVAFRRMSA-NSMILESNC1=NC=C(C=C1C(=O)NC12CCC(O)(CC1)CC2)C1=CC=C(C=C1)[C@@]12C[C@@H]1CN(C2)C1CCOCC1

Targets

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Zilurgisertib, and which of those have an active Phase 3 trial?

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