Golexanolone
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Golexanolone
- DrugBank Accession Number
- DB18200
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 329.484
Monoisotopic: 329.235479242 - Chemical Formula
- C21H31NO2
- Synonyms
- Androstan-17-one, 3-ethynyl-3-hydroxy-, oxime, (3.beta.,5.alpha.,17e)-
- External IDs
- GR 3027
- GR-3027
- GR3027
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 9C48F08TP2
- CAS number
- 2089238-18-4
- InChI Key
- FFIBGVYTWNPLPN-BZLGYYABSA-N
- InChI
- InChI=1S/C21H31NO2/c1-4-21(23)12-11-19(2)14(13-21)5-6-15-16-7-8-18(22-24)20(16,3)10-9-17(15)19/h1,14-17,23-24H,5-13H2,2-3H3/b22-18+/t14-,15-,16+,17-,19-,20+,21-/m1/s1
- IUPAC Name
- (1E,3aS,3bR,5aS,7S,9aS,9bS,11aS)-7-ethynyl-1-(hydroxyimino)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-ol
- SMILES
- [H][C@@]12CC\C(=N/O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@@](O)(CC[C@]12C)C#C
References
- General References
- Not Available
- External Links
- ChemSpider
- 76826990
- Wikipedia
- Golexanolone
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 3.93 Chemaxon pKa (Strongest Acidic) 11.52 Chemaxon pKa (Strongest Basic) 2.06 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 52.82 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 95.1 m3·mol-1 Chemaxon Polarizability 38.89 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 13, 2023 19:56 / Updated at September 15, 2023 10:38