Golexanolone

DB18200InvestigationalSmall molecule

Golexanolone: Overview.

Mechanism: Pharmacologically active on GABA(A) Receptor
Curator reviewed
Formula / weight: C₂₁H₃₁NO₂ · 329.484 g/mol (avg)
Also known as: Androstan-17-one, 3-ethynyl-3-hydroxy-, oxime, (3.beta.,5.alpha.,17e)-
Code names: GR-3027

Resolves to

Compound

Structure

InChIKeyFFIBGVYTWNPLPN-BZLGYYABSA-NSMILES[H][C@@]12CC\C(=N/O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@@](O)(CC[C@]12C)C#C

What you can answer from here — as of July 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which companies are running trials of Golexanolone, in which indications and phases, and which of those programs are still active?

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