LP-184

DB18215InvestigationalSmall molecule

LP-184: Overview.

Mechanism: Pharmacologically active on Prostaglandin reductase 1
Curator reviewed
Formula / weight: C₁₆H₂₀N₂O₄ · 304.346 g/mol (avg)
Also known as: (R)-1-HYDROXY-1-((6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXO-6',7'-DIHYDROSPIRO(CYCLOPROPANE-1,5'-INDEN)-3'-YL)METHYL)UREA · Hydroxyurea methylacylfulvene · N-(((6'R)-6',7'-DIHYDRO-6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXOSPIRO(CYCLOPROPANE-1,5'-(5H)INDEN)-3'-YL)METHYL)-N-HYDROXYUREA · N-HYDROXY-N-(METHYLACYLFULVENE)UREA · UREA, N-(((6'R)-6',7'-DIHYDRO-6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXOSPIRO(CYCLOPROPANE-1,5'-(5H)INDEN)-3'-YL)METHYL)-N-HYDROXY-
Code names: LP-184

Resolves to

Compound

Structure

InChIKeyVWMPVAZEBAKLFR-HNNXBMFYSA-NSMILESCC1=C(CN(O)C(N)=O)C2=C(C)C3(CC3)[C@@](C)(O)C(=O)C2=C1

Targets

What you can answer from here — as of October 29, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with LP-184, and which of those have an active Phase 3 trial?

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