Mefuparib

DB18248ExperimentalSmall molecule

Mefuparib: Overview.

Mechanism: Pharmacologically active on Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase 2, and Poly [ADP-ribose] polymerases
Curator reviewed
Formula / weight: C₁₇H₁₅FN₂O₂ · 298.317 g/mol (avg)
Also known as: 5-fluoro-2-(4-((methylamino)methyl)phenyl)-7-benzofurancarboxamide · Cvl-218 free base

Resolves to

Compound

Structure

InChIKeyROBJKLPZIPNAMV-UHFFFAOYSA-NSMILESCNCC1=CC=C(C=C1)C1=CC2=CC(F)=CC(C(N)=O)=C2O1

Targets

What you can answer from here — as of July 09, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Mefuparib, and which of those have an active Phase 3 trial?

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