Fobrepodacin
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Fobrepodacin
- DrugBank Accession Number
- DB18409
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 508.447
Monoisotopic: 508.163547742 - Chemical Formula
- C21H26FN6O6P
- Synonyms
- N-ethyl-n'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2r)-tetrahydro-2-furanyl)-1h-benzimidazol-2-yl)urea
- SPR-720 FREE ACID
- Urea, n-ethyl-n'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2r)-tetrahydro-2-furanyl)-1h-benzimidazol-2-yl)-
- Vxc-486 phosphate
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key Fobrepodacin sodium JX82N6UWU3 1536471-76-7 LZPLFZIOJZSXGF-PFEQFJNWSA-M
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 1NL76YUU6E
- CAS number
- 1384984-31-9
- InChI Key
- COTQDURISRILOR-CQSZACIVSA-N
- InChI
- InChI=1S/C21H26FN6O6P/c1-4-23-20(29)28-19-26-13-8-12(16(22)15(17(13)27-19)14-6-5-7-33-14)11-9-24-18(25-10-11)21(2,3)34-35(30,31)32/h8-10,14H,4-7H2,1-3H3,(H2,30,31,32)(H3,23,26,27,28,29)/t14-/m1/s1
- IUPAC Name
- {[2-(5-{2-[(ethylcarbamoyl)amino]-6-fluoro-7-[(2R)-oxolan-2-yl]-1H-1,3-benzodiazol-5-yl}pyrimidin-2-yl)propan-2-yl]oxy}phosphonic acid
- SMILES
- [H][C@@]1(CCCO1)C1=C2NC(NC(=O)NCC)=NC2=CC(=C1F)C1=CN=C(N=C1)C(C)(C)OP(O)(O)=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 28653367
- BindingDB
- 50112815
- ChEMBL
- CHEMBL2221212
- ZINC
- ZINC000095566061
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 0.93 Chemaxon pKa (Strongest Acidic) 1.38 Chemaxon pKa (Strongest Basic) 2.4 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 5 Chemaxon Polar Surface Area 171.58 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 124.83 m3·mol-1 Chemaxon Polarizability 50.68 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 21, 2023 22:28 / Updated at September 28, 2023 05:48