CFT-8634

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DB18443InvestigationalSmall molecule

CFT-8634: Overview.

Formula / weight: C₃₇H₄₅F₃N₆O₅ · 710.799 g/mol (avg)
Also known as: 2,6-PIPERIDINEDIONE, 3-((4-(4-((4S)-1-((4-(1,6-DIHYDRO-1,4,5-TRIMETHYL-6-OXO-3-PYRIDINYL)-2,6-DIMETHOXYPHENYL)METHYL)-3,3-DIFLUORO-4-PIPERIDINYL)-1-PIPERAZINYL)-3-FLUOROPHENYL)AMINO)-, (3S)-
Code names: CFT-8634

Resolves to

Compound

UNIIAW8PEP3VZ3CAS2704617-96-7ChEMBLCHEMBL5095228

Structure

InChIKeyGNRGNRCQXHMQQV-ZQAZVOLISA-NSMILESCOC1=CC(=CC(OC)=C1CN1CC[C@H](N2CCN(CC2)C2=CC=C(N[C@H]3CCC(=O)NC3=O)C=C2F)C(F)(F)C1)C1=CN(C)C(=O)C(C)=C1C

What you can answer from here — as of October 28, 2025

1Clinical trialPhase, status and sponsor resolved per trial

Which companies are running trials of CFT-8634, in which indications and phases, and which of those programs are still active?

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