DSP-5336

DB18514InvestigationalSmall molecule

DSP-5336 is a menin inhibitor.

Mechanism: Pharmacologically active on Histone-lysine N-methyltransferase 2A and Menin
Curator reviewed
Formula / weight: C₃₃H₄₃FN₆O₃ · 590.744 g/mol (avg)
Also known as: BENZAMIDE, 5-FLUORO-2-((4-(7-(((1S,3S,4R)-5-METHYLENE-2-AZABICYCLO(2.2.2)OCT-3-YL)CARBONYL)-2,7-DIAZASPIRO(3.5)NON-2-YL)-5-PYRIMIDINYL)OXY)-N,N-BIS(1-METHYLETHYL)-
Code names: DSP-5336

Resolves to

Compound

Structure

InChIKeyJQHJEDMMWUIYCE-FVVBACEJSA-NSMILESCC(C)N(C(C)C)C(=O)C1=CC(F)=CC=C1OC1=CN=CN=C1N1CC2(C1)CCN(CC2)C(=O)[C@H]1N[C@H]2CC[C@@H]1C(=C)C2

Targets

What you can answer from here — as of July 09, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with DSP-5336, and which of those have an active Phase 3 trial?

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