DM-1157
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- DM-1157
- DrugBank Accession Number
- DB18600
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 487.05
Monoisotopic: 486.2298727 - Chemical Formula
- C28H31ClN6
- Synonyms
- 4-quinolinamine, 7-chloro-n-(3-(4-((di-2-pyridinylmethyl)amino)-1-piperidinyl)propyl)-
- External IDs
- DM-1157
- DM1157
- PL-69
- PL69
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 6X58GJ0RMS
- CAS number
- 1239953-66-2
- InChI Key
- QRCZXFIANKOFOR-UHFFFAOYSA-N
- InChI
- InChI=1S/C28H31ClN6/c29-21-8-9-23-24(10-16-33-27(23)20-21)30-15-5-17-35-18-11-22(12-19-35)34-28(25-6-1-3-13-31-25)26-7-2-4-14-32-26/h1-4,6-10,13-14,16,20,22,28,34H,5,11-12,15,17-19H2,(H,30,33)
- IUPAC Name
- N-[3-(4-{[bis(pyridin-2-yl)methyl]amino}piperidin-1-yl)propyl]-7-chloroquinolin-4-amine
- SMILES
- ClC1=CC2=NC=CC(NCCCN3CCC(CC3)NC(C3=CC=CC=N3)C3=CC=CC=N3)=C2C=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 26350439
- ChEMBL
- CHEMBL1254709
- ZINC
- ZINC000043205091
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 3.62 Chemaxon pKa (Strongest Basic) 9.06 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 65.97 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 141.78 m3·mol-1 Chemaxon Polarizability 55.25 Å3 Chemaxon Number of Rings 5 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at October 03, 2023 22:48 / Updated at October 05, 2023 17:34