Celastrol

DB18736ExperimentalSmall molecule

Celastrol is a pentacyclic triterpenoid isolated from the root extracts of Tripterygium wilfordii.

Chemical structure of Celastrol
Formula / weight
C29H38O4 · 450.619 g/mol (avg)
Also known as
24-nor-d:a-friedooleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo- · 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, (9.beta.,13.alpha.,14.beta.,20.alpha.)- · Tripterin
Code names
NSC-70931

Resolves to

Compound
UNIIL8GG98663LCAS34157-83-0ChEMBLCHEMBL301982ChEBI63959
Structure
InChIKeyKQJSQWZMSAGSHN-JJWQIEBTSA-NSMILES[H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(O)=O
Targets
P01375TNFP01584IL1B

What you can answer from here — as of March 06, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
3+ReferencesStructured and connected to the statements they support
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