| DB00005 | Etanercept | approved, investigational | yes | antibody | Details |
| DB00051 | Adalimumab | approved, experimental | yes | antibody | Details |
| DB00065 | Infliximab | approved | yes | inhibitor | Details |
| DB01041 | Thalidomide | approved, investigational, withdrawn | yes | inhibitor | Details |
| DB00608 | Chloroquine | approved, investigational, vet_approved | unknown | inhibitor | Details |
| DB01407 | Clenbuterol | approved, investigational, vet_approved | unknown | other/unknown | Details |
| DB01411 | Pranlukast | investigational | unknown | other/unknown | Details |
| DB01427 | Amrinone | approved | unknown | inhibitor | Details |
| DB05207 | SD118 | investigational | unknown | | Details |
| DB05218 | PN0621 | investigational | unknown | | Details |
| DB05017 | YSIL6 | investigational | unknown | | Details |
| DB05303 | OMS-103HP | investigational | unknown | | Details |
| DB04956 | Afelimomab | investigational | unknown | | Details |
| DB05412 | Talmapimod | investigational | unknown | | Details |
| DB05470 | VX-702 | investigational | unknown | | Details |
| DB05744 | CRx-139 | investigational | unknown | | Details |
| DB05767 | Andrographolide | investigational | unknown | | Details |
| DB05758 | CYT007-TNFQb | investigational | unknown | | Details |
| DB05869 | Ethyl pyruvate | investigational | unknown | | Details |
| DB05879 | AME-527 | investigational | unknown | | Details |
| DB05968 | PR-104 | investigational | unknown | | Details |
| DB11967 | Binimetinib | approved, investigational | unknown | | Details |
| DB05513 | Atiprimod | investigational | unknown | | Details |
| DB05992 | Plinabulin | investigational | unknown | | Details |
| DB06495 | Onercept | investigational | unknown | | Details |
| DB06444 | Dexanabinol | investigational | unknown | | Details |
| DB08904 | Certolizumab pegol | approved | yes | neutralizer | Details |
| DB08910 | Pomalidomide | approved | yes | inhibitor | Details |
| DB06674 | Golimumab | approved | yes | antibody | Details |
| DB00668 | Epinephrine | approved, vet_approved | unknown | antagonistagonist | Details |
| DB00852 | Pseudoephedrine | approved | unknown | inhibitor | Details |
| DB12140 | Dilmapimod | investigational | unknown | | Details |
| DB09221 | Polaprezinc | experimental | unknown | inhibitor | Details |
| DB10770 | Foreskin fibroblast (neonatal) | approved | unknown | agonist | Details |
| DB10772 | Foreskin keratinocyte (neonatal) | approved | yes | agonist | Details |
| DB13751 | Glycyrrhizic acid | approved, experimental | yes | antagonist | Details |
| DB11752 | Bryostatin 1 | investigational | unknown | inducer | Details |