Interleukin-1 beta

BE0001051ProteinHumansIL1B

Potent pro-inflammatory cytokine (PubMed:10653850, PubMed:12794819, PubMed:28331908, PubMed:3920526). It is acted on by 21 drugs in DrugBank.

Gene name
IL1B
UniProtKB entry
P01584Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
269 residues · 30,748 Da
Also known as
Catabolin · IL-1 beta · IL1F2

Resolves to

Protein
UniProtP01584UniProt nameIL1B_HUMAN
Gene
HGNCHGNC:5992NCBI Gene3553GenBank307043GeneCardsIL1B
Pharmacology
KEGGhsa:3553
Structure
PDB1HIBPDB1I1BPDB1IOB
Drugs

What you can answer from here — as of September 07, 2019

21DrugsApproved to experimental, with action, bond type and pharmacological action
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27Clinical trialsTrials of drugs acting on it, by phase and status
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37GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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52+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-1 beta, how selective are they, and which programs against it are still in active trials?

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