Ibuzatrelvir

DB19451InvestigationalSmall molecule

Ibuzatrelvir is under investigation in clinical trial NCT06679140 (A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized but...

Mechanism: Pharmacologically active on Replicase polyprotein 1ab
Curator reviewed
Formula / weight: C₂₁H₃₀F₃N₅O₅ · 489.496 g/mol (avg)
Code names: PF-07817883

Resolves to

Compound

UNIIKZ2X7QH2VTCAS2755812-39-4ChEMBLCHEMBL5591580ChEBI759855PubChem163362000

Structure

InChIKeyWGNWEPPRWQKSKI-AIEDFZFUSA-NSMILESCOC(=O)N[C@H](C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N)C(F)(F)F)C(C)(C)C

Targets

P0C6X7repP0DTD1rep

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

11Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Ibuzatrelvir, and which of those have an active Phase 3 trial?

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