Umibecestat

DB19898ExperimentalSmall molecule

Umibecestat is a small molecule drug. The usage of the INN stem '-becestat' in the name indicates that Umibecestat is a beta secretase inhibitor. Umibecestat has a monoisotopic molecular weight...

Mechanism: Pharmacologically active on Beta-secretase 1
Curator reviewed
Formula / weight: C₁₉H₁₅ClF₇N₅O₂ · 513.8 g/mol (avg)
Code names: CNP520-NXA · NVP-CNP520-NXA

Resolves to

Compound

UNII4612B80545CAS1387560-01-1ChEMBLCHEMBL3670375

Structure

InChIKeyPSBBWFNMHDUTRH-DLBZAZTESA-NSMILESC[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)C1=NC(NC(=O)C2=C(Cl)C=C(C=N2)C(F)(F)F)=CC=C1F

Targets

P56817BACE1Q9Y5Z0BACE2

What you can answer from here — as of August 31, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Umibecestat, and which of those have an active Phase 3 trial?

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