Epertinib

DB20062ExperimentalSmall molecule

Epertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Epertinib is a epidermal growth factor receptor (EGFR) inhibitor. Epertinib has a... Epertinib has a monoisotopic molecular weight of 559.18 Da.

Mechanism: Pharmacologically active on Receptor tyrosine-protein kinase erbB-2 and Epidermal growth factor receptor
Curator reviewed
Formula / weight: C₃₀H₂₇ClFN₅O₃ · 560.03 g/mol (avg)
Code names: S-222611

Resolves to

Compound

UNII60OIK33ZQRCAS908305-13-5

Structure

InChIKeyIBCIAMOTBDGBJN-NRLRZRKLSA-NSMILESCC#C\C(=N/OC[C@H]1COCCN1)C1=CC2=C(NC3=CC(Cl)=C(OCC4=CC(F)=CC=C4)C=C3)N=CN=C2C=C1

Targets

P04626ERBB2P00533EGFR

What you can answer from here — as of August 31, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Epertinib, and which of those have an active Phase 3 trial?

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