Heliomycin

DB20233ExperimentalSmall molecule

Heliomycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Heliomycin is a antibiotic, produced by Streptomyces strain. Heliomycin has a monoisotopic...

Mechanism: Pharmacologically active on NAD-dependent protein deacetylase sirtuin-1, Histone deacetylase, and E3 ubiquitin-protein ligase pellino homolog 1
Curator reviewed
Formula / weight: C₂₂H₁₆O₆ · 376.364 g/mol (avg)
Code names: ANTIBIOTIC A-3733A · GELIOMYCIN

Resolves to

Compound

UNII7N3A092A5XCAS20004-62-0ChEMBLCHEMBL1320139ChEBI29671KEGGC12080

Structure

InChIKeyABLACSIRCKEUOB-UHFFFAOYSA-NSMILESCC1=C2C(O)=CC3=C4C2=C(C(O)=C1)C(=O)C1=C4C(=C(O)C=C1O)C(=O)C3(C)C

Targets

Q96EB6SIRT1Q96FA3PELI1

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Heliomycin, and which of those have an active Phase 3 trial?

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