Balamapimod

DB20250ExperimentalSmall molecule

Balamapimod is a small molecule drug. The usage of the INN stem '-mapimod' in the name indicates that Balamapimod is a mitogen-activated protein (MAP) kinase inhibitor. Balamapimod has a monoisotopic...

Mechanism: Pharmacologically active on Dual specificity mitogen-activated protein kinase kinase 1 and Dual specificity mitogen-activated protein kinase kinase 2
Curator reviewed
Formula / weight: C₃₀H₃₂ClN₇OS · 574.14 g/mol (avg)
Code names: MKI-833

Resolves to

Compound

UNII7Y0IV7N95QCAS863029-99-6ChEMBLCHEMBL2104954ChEBI751137PubChem11478684

Structure

InChIKeyCVAKNHIXTWLGJO-UHFFFAOYSA-NSMILESCOC1=C(C=C2N=CC(C#N)=C(NC3=CC=C(SC4=NC=CN4C)C(Cl)=C3)C2=C1)N1CCC(CC1)N1CCCC1

Targets

Q02750MAP2K1P36507MAP2K2

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Balamapimod, and which of those have an active Phase 3 trial?

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