Mespirenone

DB20625ExperimentalSmall molecule

Mespirenone is a small molecule drug. The usage of the INN stem '-renone' in the name indicates that Mespirenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. Mespirenone has... Mespirenone has a monoisotopic molecular weight of 426.19 Da.

Mechanism: Pharmacologically active on Mineralocorticoid receptor
Curator reviewed
Formula / weight: C₂₅H₃₀O₄S · 426.57 g/mol (avg)

Resolves to

Compound

UNIIE91TME2I23CAS87952-98-5ChEMBLCHEMBL1908314

Structure

InChIKeyCPHJTSJQUQZOLJ-ISIDMKFXSA-NSMILES[H][C@@]12C[C@]1([H])[C@@]1(CCC(=O)O1)[C@@]1(C)CC[C@@]3([H])[C@@]([H])([C@@H](CC4=CC(=O)C=C[C@]34C)SC(C)=O)[C@]21[H]

Targets

P08235NR3C2P10275AR

What you can answer from here — as of September 13, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Mespirenone, and which of those have an active Phase 3 trial?

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