Lotrafiban

DB20872ExperimentalSmall molecule

Lotrafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Lotrafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist). Lotrafiban has... Lotrafiban has a monoisotopic molecular weight of 428.24 Da.

Formula / weight: C₂₃H₃₂N₄O₄ · 428.533 g/mol (avg)

Resolves to

Compound

UNIIKLQ306I83XCAS171049-14-2ChEMBLCHEMBL356301

Structure

InChIKeyPYZOVVQJTLOHDG-FQEVSTJZSA-NSMILESCN1CC2=C(N[C@@H](CC(O)=O)C1=O)C=CC(=C2)C(=O)N1CCC(CC1)C1CCNCC1

Targets

P08514ITGA2BP05106ITGB3

What you can answer from here — as of September 20, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Lotrafiban, and which of those have an active Phase 3 trial?

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