Sibrafiban

DB21420ExperimentalSmall molecule

Sibrafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Sibrafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist). Sibrafiban has... Sibrafiban has a monoisotopic molecular weight of 420.2 Da.

Chemical structure of Sibrafiban
Formula / weight
C20H28N4O6 · 420.466 g/mol (avg)
Code names
RO-48-3657 · RO 48-3657/001

Resolves to

Compound
UNIIYUE443B0NFCAS170094-62-9ChEMBLCHEMBL435176ChEBI177667
Structure
InChIKeyWBNUCLPUOSXSNJ-ZDUSSCGKSA-NSMILESCCOC(=O)COC1CCN(CC1)C(=O)[C@H](C)NC(=O)C1=CC=C(C=C1)C(\N)=N\O
Targets
P08514ITGA2BP05106ITGB3

What you can answer from here — as of September 21, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Sibrafiban, and which of those have an active Phase 3 trial?

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