Ledaborbactam etzadroxil

DB21455InvestigationalSmall molecule

Ledaborbactam etzadroxil is a small molecule drug. The usage of the INN stem '-bactam' in the name indicates that Ledaborbactam etzadroxil is a ẞ-lactamase inhibitor. Ledaborbactam etzadroxil is under investigation... Ledaborbactam etzadroxil is under investigation in clinical trial NCT06733675 (Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination).

Mechanism: Pharmacologically active on Beta-lactamase, Beta-lactamase CTX-M, and OXA-48 carbapenemase
Curator reviewed
Formula / weight: C₁₉H₂₆BNO₇ · 391.23 g/mol (avg)
Code names: VNRX-5236 Etzadroxil · VNRX-7145

Resolves to

Compound

UNIIC5F376EKS2CAS1842399-68-1ChEMBLCHEMBL4594425

Structure

InChIKeySDTLIXWDRBWASV-HNNXBMFYSA-NSMILESCCC(CC)C(=O)OCOC(=O)C1=CC=CC2=C1OB(O)[C@H](C2)NC(=O)CC

Targets

P00811ampCA0A023W3H0OXA-48Q9F663KPC-2

What you can answer from here — as of September 16, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with Ledaborbactam etzadroxil, and which of those have an active Phase 3 trial?

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