Solute carrier organic anion transporter family member 1B3

BE0003659ProteinHumansSLCO1B3

Mediates the Na(+)-independent uptake of organic anions (PubMed:10779507, PubMed:15159445, PubMed:17412826). It is acted on by 176 drugs in DrugBank.

Gene name
SLCO1B3
UniProtKB entry
Q9NPD5Swiss-Prot
Cellular location
Basolateral cell membrane
Residues / weight
702 residues · 77,402 Da
Also known as
Liver-specific organic anion transporter 2 · LST-2 · LST2 · OATP-8 · OATP1B3

Resolves to

Protein
UniProtQ9NPD5UniProt nameSO1B3_HUMAN
Gene
HGNCHGNC:10961NCBI Gene28234GenBank9187497GeneCardsSLCO1B3
Pharmacology
IUPHAR/GtoPdb1221KEGGhsa:28234
Structure
PDB8PG0
Drugs

What you can answer from here — as of September 07, 2019

176DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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248+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier organic anion transporter family member 1B3, how selective are they, and which programs against it are still in active trials?

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