R-(-)-Gossypol acetic acid

DB31698InvestigationalSmall molecule

R-(-)-Gossypol acetic acid: Overview.

Mechanism: Pharmacologically active on Apoptosis regulator Bcl-2, Bcl-2-like protein 1, and Induced myeloid leukemia cell differentiation protein Mcl-1
Curator reviewed
Formula / weight: C₃₂H₃₄O₁₀ · 578.614 g/mol (avg)

Resolves to

Compound

Structure

InChIKeyNIOHNDKHQHVLKA-UHFFFAOYSA-NSMILESCC(O)=O.CC(C)C1=C2C=C(C)C(=C(O)C2=C(C=O)C(O)=C1O)C1=C(O)C2=C(C=O)C(O)=C(O)C(C(C)C)=C2C=C1C

Targets

What you can answer from here — as of August 31, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

9Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with R-(-)-Gossypol acetic acid, and which of those have an active Phase 3 trial?

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