Y-33075

DB33614ExperimentalSmall molecule

Y-33075: Overview.

Mechanism: Pharmacologically active on Rho-associated protein kinase 1 and Rho-associated protein kinase 2
Curator reviewed
Formula / weight: C₁₆H₁₆N₄O · 280.331 g/mol (avg)
Also known as: Y-39983 · Y-39983 free base

Resolves to

Compound

Structure

InChIKeyJTVBXQAYBIJXRP-SNVBAGLBSA-NSMILESC[C@@H](N)C1=CC=C(C=C1)C(=O)NC1=C2C=CNC2=NC=C1

Targets

What you can answer from here — as of October 19, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Y-33075, and which of those have an active Phase 3 trial?

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