Chlorpromazine hydrochlorideProduct ingredient for Chlorpromazine
- Name
- Chlorpromazine hydrochloride
- Drug Entry
- Chlorpromazine
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
- Accession Number
- DBSALT000026
- Structure
- Synonyms
- Chlorpromazine HCl
- UNII
- 9WP59609J6
- CAS Number
- 69-09-0
- Weight
- Average: 355.325
Monoisotopic: 354.072424754 - Chemical Formula
- C17H20Cl2N2S
- InChI Key
- FBSMERQALIEGJT-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
- IUPAC Name
- [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine hydrochloride
- SMILES
- Cl.CN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(Cl)C=C2
- External Links
- KEGG Compound
- C07952
- PubChem Compound
- 6240
- ChemSpider
- 6004
- ChEBI
- 3649
- ChEMBL
- CHEMBL1713
- Wikipedia
- Chlorpromazine
- Predicted Properties
Property Value Source Water Solubility 0.00417 mg/mL ALOGPS logP 5.18 ALOGPS logP 4.54 Chemaxon logS -4.9 ALOGPS pKa (Strongest Basic) 9.2 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 6.48 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 93.76 m3·mol-1 Chemaxon Polarizability 35.42 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon