Kanamycin sulfateProduct ingredient for Kanamycin
- Name
- Kanamycin sulfate
- Drug Entry
- Kanamycin
Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
- Accession Number
- DBSALT000401
- Structure
- Synonyms
- Kanamycin A sulfate / Kanamycin A sulphate / Kanamycin acid sulfate / Kanamycin monosulfate / Kanamycin sulphate
- UNII
- J80EX28SMQ
- CAS Number
- 25389-94-0
- Weight
- Average: 582.577
Monoisotopic: 582.205437256 - Chemical Formula
- C18H38N4O15S
- InChI Key
- OOYGSFOGFJDDHP-KMCOLRRFSA-N
- InChI
- InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1
- IUPAC Name
- (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol; sulfuric acid
- SMILES
- OS(O)(=O)=O.[H][C@@]1(N)C[C@]([H])(N)[C@@]([H])(O[C@@]2([H])O[C@]([H])(CN)[C@@]([H])(O)[C@]([H])(O)[C@@]2([H])O)[C@]([H])(O)[C@@]1([H])O[C@@]1([H])O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(N)[C@@]1([H])O
- External Links
- KEGG Compound
- C08046
- PubChem Compound
- 441374
- ChemSpider
- 390116
- ChEBI
- 6109
- ChEMBL
- CHEMBL1446
- Wikipedia
- Kanamycin_A
- Predicted Properties
Property Value Source Water Solubility 92.3 mg/mL ALOGPS logP -3.1 ALOGPS logP -7.1 Chemaxon logS -0.72 ALOGPS pKa (Strongest Acidic) 12.11 Chemaxon pKa (Strongest Basic) 9.54 Chemaxon Physiological Charge 4 Chemaxon Hydrogen Acceptor Count 15 Chemaxon Hydrogen Donor Count 11 Chemaxon Polar Surface Area 282.61 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 106.13 m3·mol-1 Chemaxon Polarizability 47.29 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon