Methdilazine HydrochlorideProduct ingredient for Methdilazine
- Name
- Methdilazine Hydrochloride
- Drug Entry
- Methdilazine
Methdilazine is a phenothiazine compound with antihistaminic activity. It is used in the treatment of various dermatoses to relieve pruritus.
- Accession Number
- DBSALT000486
- Structure
Structure for Methdilazine Hydrochloride (DBSALT000486)
- Synonyms
- Methdilazine HCl
- UNII
- T0GSO02UEZ
- CAS Number
- 1229-35-2
- Weight
- Average: 332.891
Monoisotopic: 332.111397079 - Chemical Formula
- C18H21ClN2S
- InChI Key
- IEISBKIVLDXSMZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H20N2S.ClH/c1-19-11-10-14(12-19)13-20-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)20;/h2-9,14H,10-13H2,1H3;1H
- IUPAC Name
- 10-[(1-methylpyrrolidin-3-yl)methyl]-10H-phenothiazine hydrochloride
- SMILES
- Cl.CN1CCC(CN2C3=CC=CC=C3SC3=CC=CC=C23)C1
- External Links
- PubChem Compound
- 14676
- ChemSpider
- 14008
- ChEBI
- 140855
- ChEMBL
- CHEMBL1200532
- Wikipedia
- Methdilazine
- Predicted Properties
Property Value Source Water Solubility 0.0147 mg/mL ALOGPS logP 4.56 ALOGPS logP 3.94 Chemaxon logS -4.3 ALOGPS pKa (Strongest Basic) 8.81 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 6.48 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 91.64 m3·mol-1 Chemaxon Polarizability 33.45 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon