Procarbazine hydrochlorideProduct ingredient for Procarbazine
- Name
- Procarbazine hydrochloride
- Drug Entry
- Procarbazine
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
- Accession Number
- DBSALT000731
- Structure
- Synonyms
- Procarbazine HCl
- UNII
- XH0NPH5ZX8
- CAS Number
- 366-70-1
- Weight
- Average: 294.221
Monoisotopic: 293.106167723 - Chemical Formula
- C12H21Cl2N3O
- InChI Key
- OCSSHHHAHMCFDV-UHFFFAOYSA-N
- InChI
- InChI=1S/C12H19N3O.2ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);2*1H
- IUPAC Name
- 4-[(2-methylhydrazin-1-yl)methyl]-N-(propan-2-yl)benzamide dihydrochloride
- SMILES
- Cl.Cl.CNNCC1=CC=C(C=C1)C(=O)NC(C)C
- External Links
- PubChem Compound
- 23616826
- ChemSpider
- 19953253
- Wikipedia
- Procarbazine
- Predicted Properties
Property Value Source Water Solubility 0.228 mg/mL ALOGPS logP 0.53 ALOGPS logP 0.99 Chemaxon logS -3 ALOGPS pKa (Strongest Acidic) 15.03 Chemaxon pKa (Strongest Basic) 5.56 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 53.16 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 86.98 m3·mol-1 Chemaxon Polarizability 25.81 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon