Ipodate sodiumProduct ingredient for Iopodic acid
- Name
- Ipodate sodium
- Drug Entry
- Iopodic acid
Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6.1 Due to its particular structure, it presents a high degree of lipid solubility and a radiopaque property. It was developed and filed to the FDA by the company BRACCO. This drug was approved on March 15, 1962 but it is nowadays discontinued from the FDA and Health Canada. On September 22, 1981, ipodate was submitted again by the company Schering AG but it is currently under an inactive status.7
- Accession Number
- DBSALT001318
- Structure
- Synonyms
- Iopodate sodium / Ipodate sodium salt / Oragrafin sodium / Sodium iopodate / Sodium ipodate
- External IDs
- NSC-106962
- UNII
- F316LLW9WW
- CAS Number
- 1221-56-3
- Weight
- Average: 619.943
Monoisotopic: 619.79306 - Chemical Formula
- C12H12I3N2NaO2
- InChI Key
- ZFHZUGUCWJVEQC-UHFFFAOYSA-M
- InChI
- InChI=1S/C12H13I3N2O2.Na/c1-17(2)6-16-12-9(14)5-8(13)7(11(12)15)3-4-10(18)19;/h5-6H,3-4H2,1-2H3,(H,18,19);/q;+1/p-1
- IUPAC Name
- sodium 3-(3-{[(dimethylamino)methylidene]amino}-2,4,6-triiodophenyl)propanoate
- SMILES
- [Na+].CN(C)C=NC1=C(I)C=C(I)C(CCC([O-])=O)=C1I
- External Links
- ChemSpider
- 20473671
- ChEMBL
- CHEMBL3184539
- Wikipedia
- Ipodate_sodium
- Predicted Properties
Property Value Source Water Solubility 0.00615 mg/mL ALOGPS logP 3.34 ALOGPS logP 3.4 Chemaxon logS -5 ALOGPS pKa (Strongest Acidic) 1.99 Chemaxon pKa (Strongest Basic) 4.16 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 55.73 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 115.75 m3·mol-1 Chemaxon Polarizability 39.79 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon