Metralindole hydrochlorideProduct ingredient for Metralindole
- Name
- Metralindole hydrochloride
- Drug Entry
- Metralindole
Metralindole, also known as Inkazan, is similar in structure and pharmacology to pirlindole. It functions as a reversible inhibitor of monoamine oxidase A. In Russia, this drug was investigated for potential antidepressant activity.
- Accession Number
- DBSALT001789
- Structure
- Synonyms
- Metralindole HCl
- UNII
- M15TM76Y3L
- CAS Number
- 53734-79-5
- Weight
- Average: 291.78
Monoisotopic: 291.1138399 - Chemical Formula
- C15H18ClN3O
- InChI Key
- RQQVSZWEVNAKGW-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H17N3O.ClH/c1-17-7-8-18-13-4-3-10(19-2)9-12(13)11-5-6-16-15(17)14(11)18;/h3-4,9H,5-8H2,1-2H3;1H
- IUPAC Name
- 12-methoxy-4-methyl-1,4,6-triazatetracyclo[7.6.1.0⁵,¹⁶.0¹⁰,¹⁵]hexadeca-5,9(16),10(15),11,13-pentaene hydrochloride
- SMILES
- Cl.COC1=CC2=C(C=C1)N1CCN(C)C3=NCCC2=C13
- External Links
- ChemSpider
- 149758
- ChEMBL
- CHEMBL1388946
- Predicted Properties
Property Value Source Water Solubility 0.367 mg/mL ALOGPS logP 1.62 ALOGPS logP 1.61 Chemaxon logS -2.8 ALOGPS pKa (Strongest Basic) 8.95 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 29.76 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 75.95 m3·mol-1 Chemaxon Polarizability 28.97 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon