Technetium Tc-99m medronate disodiumProduct ingredient for Technetium Tc-99m medronate
- Name
- Technetium Tc-99m medronate disodium
- Drug Entry
- Technetium Tc-99m medronate
Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. Like other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way localizes the drug to bone for delineation of areas of altered osteogenesis. Following intravenous injection, single photon emission computed tomography (SPECT) is performed to detect the gamma ray emmitted by the decay of Technetium-99m to Technetium-99.
- Accession Number
- DBSALT001857
- Structure
- Synonyms
- Not Available
- UNII
- V3V5VW82PO
- CAS Number
- 65871-22-9
- Weight
- Average: 533.803
Monoisotopic: 533.73161637 - Chemical Formula
- C2H4Na4O12P4Tc
- InChI Key
- AXNBRPOESGBANA-KTTJZPQESA-F
- InChI
- InChI=1S/2CH6O6P2.4Na.Tc/c2*2-8(3,4)1-9(5,6)7;;;;;/h2*1H2,(H2,2,3,4)(H2,5,6,7);;;;;/q;;4*+1;+4/p-8/i;;;;;;1+1
- IUPAC Name
- (⁹⁸Tc)technetium(4+) ion tetrasodium di(phosphonatomethyl)phosphonate
- SMILES
- [Na+].[Na+].[Na+].[Na+].[98Tc+4].[O-]P([O-])(=O)CP([O-])([O-])=O.[O-]P([O-])(=O)CP([O-])([O-])=O
- External Links
- ChemSpider
- 34994626
- Predicted Properties
Property Value Source Water Solubility 42.0 mg/mL ALOGPS logP -0.11 ALOGPS logP -2.4 Chemaxon logS -0.8 ALOGPS pKa (Strongest Acidic) 1.27 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 126.38 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 23.39 m3·mol-1 Chemaxon Polarizability 10.06 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon