Landiolol hydrochlorideProduct ingredient for Landiolol
- Name
- Landiolol hydrochloride
- Drug Entry
- Landiolol
Landiolol is a rapid-acting beta-blocker used for rapid ventricular rate control.
- Accession Number
- DBSALT002156
- Structure
- Synonyms
- Not Available
- UNII
- G8HQ634Y17
- CAS Number
- 144481-98-1
- Weight
- Average: 546.06
Monoisotopic: 545.250393 - Chemical Formula
- C25H40ClN3O8
- InChI Key
- DLPGJHSONYLBKP-IKGOIYPNSA-N
- InChI
- InChI=1S/C25H39N3O8.ClH/c1-25(2)35-18-22(36-25)17-34-23(30)8-5-19-3-6-21(7-4-19)33-16-20(29)15-26-9-10-27-24(31)28-11-13-32-14-12-28;/h3-4,6-7,20,22,26,29H,5,8-18H2,1-2H3,(H,27,31);1H/t20-,22+;/m0./s1
- IUPAC Name
- N-(2-{[(2S)-3-[4-(3-{[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy}-3-oxopropyl)phenoxy]-2-hydroxypropyl]amino}ethyl)morpholine-4-carboximidic acid hydrochloride
- SMILES
- Cl.[H][C@](O)(CNCCN=C(O)N1CCOCC1)COC1=CC=C(CCC(=O)OC[C@]2([H])COC(C)(C)O2)C=C1
- External Links
- ChemSpider
- 144176
- ChEBI
- 31760
- ChEMBL
- CHEMBL2362410
- Predicted Properties
Property Value Source Water Solubility 0.163 mg/mL ALOGPS logP 0.95 ALOGPS logP -0.33 Chemaxon logS -3.5 ALOGPS pKa (Strongest Acidic) -3.4 Chemaxon pKa (Strongest Basic) 15.05 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 10 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 131.31 Å2 Chemaxon Rotatable Bond Count 14 Chemaxon Refractivity 132.21 m3·mol-1 Chemaxon Polarizability 56.19 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon