Guanoxan sulfateProduct ingredient for Guanoxan
- Name
- Guanoxan sulfate
- Drug Entry
- Guanoxan
Guanoxan is an antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage. Guanoxan was approved in the UK but was withdrawn from the market due to hepatotoxicity.
- Accession Number
- DBSALT002676
- Structure
- Synonyms
- Guanoxan sulphate
- External IDs
- 3-01003 / Compound 1003 / P 1003 / P 3/01003 / P-1003
- UNII
- N6IT80R85G
- CAS Number
- 5714-04-5
- Weight
- Average: 512.54
Monoisotopic: 512.16893306 - Chemical Formula
- C20H28N6O8S
- InChI Key
- NSGHAKPGHCNTPS-UHFFFAOYSA-N
- InChI
- InChI=1S/2C10H13N3O2.H2O4S/c2*11-10(12)13-5-7-6-14-8-3-1-2-4-9(8)15-7;1-5(2,3)4/h2*1-4,7H,5-6H2,(H4,11,12,13);(H2,1,2,3,4)
- IUPAC Name
- bis(N-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]guanidine); sulfuric acid
- SMILES
- OS(O)(=O)=O.NC(=N)NCC1COC2=C(O1)C=CC=C2.NC(=N)NCC1COC2=C(O1)C=CC=C2
- External Links
- ChemSpider
- 20621
- ChEMBL
- CHEMBL1742462
- Predicted Properties
Property Value Source Water Solubility 1.33 mg/mL ALOGPS logP 0.1 ALOGPS logP 0.42 Chemaxon logS -2.2 ALOGPS pKa (Strongest Basic) 11.99 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 80.36 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 65.35 m3·mol-1 Chemaxon Polarizability 21.48 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon