Caramiphen hydrochlorideProduct ingredient for Caramiphen
- Name
- Caramiphen hydrochloride
- Drug Entry
- Caramiphen
Caramiphen is a cholinergic antagonist used in Parkinson's disease. Additionally, it is used, in combination with phenylpropanolamine, as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal respiratory conditions.
- Accession Number
- DBSALT002875
- Structure
- Synonyms
- Caramiphen HCl / Caramiphene hydrochloride
- UNII
- 4858SN190E
- CAS Number
- 125-85-9
- Weight
- Average: 325.88
Monoisotopic: 325.1808568 - Chemical Formula
- C18H28ClNO2
- InChI Key
- MUPNXGNOIBYHSG-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H27NO2.ClH/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16;/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3;1H
- IUPAC Name
- 2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate hydrochloride
- SMILES
- Cl.CCN(CC)CCOC(=O)C1(CCCC1)C1=CC=CC=C1
- External Links
- ChemSpider
- 60517
- ChEMBL
- CHEMBL1598472
- Predicted Properties
Property Value Source Water Solubility 0.0437 mg/mL ALOGPS logP 4.31 ALOGPS logP 4.01 Chemaxon logS -3.8 ALOGPS pKa (Strongest Basic) 8.96 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 29.54 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 86.13 m3·mol-1 Chemaxon Polarizability 34.2 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon