Periodontitis

Also known as: PERIODONTITIS / Chronic pericoronitis

DrugDrug NameDrug Description
DB00878ChlorhexidineAn antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.
DB09095DifluocortoloneA topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB01017MinocyclineA tetracycline analog used to treat a wide variety of infections in the body.
DB13261SitafloxacinA fluoroquinolone antibiotic indicated in the treatment of susceptible bacterial infections.
DB15794SolcoserylA component of calf blood indicated to improve healing of the skin, mouth, or cornea.
DrugDrug NameTargetType
DB00878ChlorhexidineBacterial outer membranetarget
DB00878ChlorhexidineSerum albumincarrier
DB09095DifluocortoloneAnnexin A3target
DB09095DifluocortoloneGlucocorticoid receptortarget
DB09095DifluocortoloneCytochrome P450 3A4enzyme
DB09095DifluocortoloneCytochrome P450 3A5enzyme
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleP-glycoprotein 1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DB01017Minocycline30S ribosomal protein S4target
DB01017Minocycline30S ribosomal protein S9target
DB01017Minocycline16S ribosomal RNAtarget
DB01017MinocyclineInterleukin-1 betatarget
DB01017MinocyclineArachidonate 5-lipoxygenasetarget
DB01017MinocyclineMatrix metalloproteinase-9target
DB01017MinocyclineVascular endothelial growth factor Atarget
DB01017MinocyclineCaspase-1target
DB01017MinocyclineCaspase-3target
DB01017MinocyclineCytochrome ctarget
DB01017MinocyclineSolute carrier family 22 member 6transporter
DB01017MinocyclineSolute carrier family 22 member 7transporter
DB01017MinocyclineOuter membrane protein Ftransporter
DB01017MinocyclineOuter membrane porin Ctransporter
DB01017MinocyclineMitogen-activated Protein Kinasestarget
DB01017MinocyclineNitric oxide synthase, inducibletarget
DB13261SitafloxacinCytochrome P450 1A2enzyme
DrugDrug NamePhaseStatusCount
DB13906Aloe vera leaf0Not Yet Recruiting1
DB14131Basic Fibroblast Growth Factor0Completed1
DB08818Hyaluronic acid1Completed1
DB14145Nepidermin1Recruiting1
DB00020Sargramostim1Completed1
DB06285Teriparatide1Completed1
DB15649Carbomer1 / 2Completed1
DB12473Taurolidine1 / 2Completed1
DB00945Acetylsalicylic acid2Completed1
DB01060Amoxicillin2Completed1
DB00126Ascorbic acid2Unknown Status1
DB01076Atorvastatin2Completed1
DB14131Basic Fibroblast Growth Factor2Completed1
DB00297Bupivacaine2Terminated1
DB11073Cetylpyridinium2Completed1
DB00878Chlorhexidine2Completed3
DB00091Cyclosporine2Completed1
DB11639Dibotermin alfa2Completed1
DB03756Doconexent2Completed1
DB00254Doxycycline2Completed1
DB00668Epinephrine2Terminated1
DB16604Fibrin2Completed1
DB00712Flurbiprofen2Completed1
DB16024Indocyanine green2Completed1
DB13178Inositol2Unknown Status1
DB00130L-Glutamine2Completed1
DB00281Lidocaine2Terminated1
DB00331Metformin2Completed1
DB00916Metronidazole2Completed2
DB00507Nitazoxanide2Completed1
DB12983Phthalocyanine2Recruiting1
DB09422Soybean oil2Completed1
DB12473Taurolidine2Completed1
DB11218Tea tree oil2Completed1
DB06244Trafermin2Completed2
DB13906Aloe vera leaf2 / 3Completed1
DB01050Ibuprofen2 / 3Completed1
DB00331Metformin2 / 3Completed1
DB01060Amoxicillin3Completed2
DB01060Amoxicillin3Recruiting1
DB00878Chlorhexidine3Not Yet Recruiting1
DB00878Chlorhexidine3Unknown Status1
DB01190Clindamycin3Completed1
DB11672Curcumin3Recruiting1
DB00254Doxycycline3Completed2
DB08818Hyaluronic acid3Not Yet Recruiting1
DB11091Hydrogen peroxide3Not Yet Recruiting1
DB00916Metronidazole3Completed2
DB00916Metronidazole3Recruiting1
DB01017Minocycline3Completed2
DB00759Tetracycline3Completed1
DB06244Trafermin3Completed2
DB08604Triclosan3Completed1
DB00945Acetylsalicylic acid4Completed1
DB00630Alendronic acid4Completed1
DB01060Amoxicillin4Completed2
DB09009Articaine4Completed1
DB00207Azithromycin4Completed1
DB11073Cetylpyridinium4Unknown Status1
DB00878Chlorhexidine4Completed5
DB00878Chlorhexidine4Not Yet Recruiting1
DB00878Chlorhexidine4Recruiting1
DB00878Chlorhexidine4Terminated1
DB00878Chlorhexidine4Unknown Status1
DB01211Clarithromycin4Completed1
DB11672Curcumin4Completed2
DB00254Doxycycline4Terminated1
DB00974Edetic acid4Completed1
DB00668Epinephrine4Completed1
DB01628Etoricoxib4Completed1
DB16604Fibrin4Completed2
DB09222Fibrinogen human4Completed1
DB08958Hexetidine4Completed1
DB08958Hexetidine4Unknown Status1
DB11571Human thrombin4Completed1
DB08818Hyaluronic acid4Completed1
DB01050Ibuprofen4Terminated1
DB00825Levomenthol4Unknown Status3
DB00281Lidocaine4Completed1
DB00916Metronidazole4Completed2
DB01017Minocycline4Completed2
DB01165Ofloxacin4Completed1
DB00641Simvastatin4Completed1
DB00624Testosterone4Withdrawn1
DB09145Water4Completed1
DB09145Water4Unknown Status1
DB00207AzithromycinNot AvailableCompleted1
DB00102BecaplerminNot AvailableCompleted1
DB01156BupropionNot AvailableCompleted1
DB11073CetylpyridiniumNot AvailableCompleted1
DB00878ChlorhexidineNot AvailableCompleted2
DB00878ChlorhexidineNot AvailableUnknown Status1
DB11639Dibotermin alfaNot AvailableCompleted1
DB00898EthanolNot AvailableCompleted1
DB00898EthanolNot AvailableUnknown Status1
DB03852EucalyptolNot AvailableUnknown Status1
DB08818Hyaluronic acidNot AvailableCompleted1
DB00825LevomentholNot AvailableUnknown Status1
DB00281LidocaineNot AvailableCompleted1
DB09543Methyl salicylateNot AvailableUnknown Status1
DB00916MetronidazoleNot AvailableCompleted1
DB00916MetronidazoleNot AvailableNot Yet Recruiting1
DB00916MetronidazoleNot AvailableUnknown Status1
DB01017MinocyclineNot AvailableNot Yet Recruiting1
DB00184NicotineNot AvailableCompleted1
DB01956TaurineNot AvailableCompleted1
DB02513ThymolNot AvailableUnknown Status1
DB01273VareniclineNot AvailableCompleted1