Refractory Non-Hodgkin's lymphoma

Also known as: Refractory Non-Hodgkin-Lymphoma / Refractory Non-Hodgkin Lymphoma / Refractory Non-Hodgkin Lympoma / Refractory Non Hodgkin Lymphoma / Non-Hodgkin's lymphoma refractory / Non-Hodgkin's lymphoma NOS refractory

DrugDrug NameDrug Description
DB00958CarboplatinA alkylating agent used to treat advanced ovarian cancer.
DB00262CarmustineAn alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
DB01073FludarabineA purine analog antimetabolite that inhibits DNA synthesis.
DB00563MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
DB06193PixantroneAn antineoplastic agent use to treat patients with relapsed or refractory aggressive Non-Hodgkin B-cell Lymphomas (NHL).
DrugDrug NameTargetType
DB00958CarboplatinDNAtarget
DB00958CarboplatinHigh affinity copper uptake protein 1transporter
DB00958CarboplatinProbable low affinity copper uptake protein 2transporter
DB00958CarboplatinXanthine dehydrogenase/oxidaseenzyme
DB00958CarboplatinMyeloperoxidaseenzyme
DB00958CarboplatinGlutathione S-transferase theta-1enzyme
DB00958CarboplatinMetallothionein-1Aenzyme
DB00958CarboplatinMetallothionein-2enzyme
DB00958CarboplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00958CarboplatinGlutathione S-transferase Penzyme
DB00958CarboplatinGlutathione S-transferase Mu 1enzyme
DB00958CarboplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00958CarboplatinCopper-transporting ATPase 1transporter
DB00958CarboplatinCopper-transporting ATPase 2transporter
DB00958CarboplatinATP-binding cassette sub-family G member 2transporter
DB00958CarboplatinCanalicular multispecific organic anion transporter 1transporter
DB00262CarmustineGlutathione reductase, mitochondrialtarget
DB00262CarmustineDNAtarget
DB00262CarmustineRNAtarget
DB01073FludarabineDNA polymerase alpha catalytic subunittarget
DB01073FludarabineRibonucleoside-diphosphate reductase large subunittarget
DB01073FludarabineEquilibrative nucleoside transporter 1transporter
DB01073FludarabineDNAtarget
DB01073FludarabineDeoxycytidine kinasetarget
DB01073FludarabineSolute carrier family 28 member 3transporter
DB00563MethotrexateDihydrofolate reductasetarget
DB00563MethotrexateAldehyde oxidaseenzyme
DB00563MethotrexateMethylenetetrahydrofolate reductaseenzyme
DB00563MethotrexateSerum albumincarrier
DB00563MethotrexateCanalicular multispecific organic anion transporter 2transporter
DB00563MethotrexateMultidrug resistance-associated protein 4transporter
DB00563MethotrexateMultidrug resistance-associated protein 1transporter
DB00563MethotrexateSolute carrier family 22 member 6transporter
DB00563MethotrexateMultidrug resistance-associated protein 7transporter
DB00563MethotrexateSolute carrier family 22 member 8transporter
DB00563MethotrexateCanalicular multispecific organic anion transporter 1transporter
DB00563MethotrexateP-glycoprotein 1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1A2transporter
DB00563MethotrexateMonocarboxylate transporter 1transporter
DB00563MethotrexateATP-binding cassette sub-family C member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B3transporter
DB00563MethotrexateSolute carrier family 22 member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1C1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 3A1transporter
DB00563MethotrexateATP-binding cassette sub-family G member 2transporter
DB00563MethotrexateSolute carrier family 22 member 7transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B1transporter
DB00563Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00563MethotrexateProton-coupled folate transportertransporter
DB00563MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB00563MethotrexateGamma-glutamyl hydrolaseenzyme
DB00563MethotrexateDihydrofolate reductaseenzyme
DB00563MethotrexateThymidylate synthaseenzyme
DB00563MethotrexateBifunctional purine biosynthesis protein PURHenzyme
DB00563MethotrexateSolute carrier organic anion transporter family member 4C1transporter
DB00563MethotrexateFolate transporter 1transporter
DB00563MethotrexateFolate receptor alphatransporter
DB00563MethotrexateCytochrome P450 3A4enzyme
DB00563MethotrexateThymidylate synthasetarget
DB00563MethotrexateBifunctional purine biosynthesis protein PURHtarget
DB00563MethotrexateFolate receptor betatransporter
DB00563MethotrexateSolute carrier family 15 member 1transporter
DB00563MethotrexateProton-coupled amino acid transporter 1transporter
DB00563MethotrexateCarboxypeptidase G2enzyme
DrugDrug NamePhaseStatusCount
DB00531Cyclophosphamide0Completed1
DB00091Cyclosporine0Completed1
DB01254Dasatinib0Recruiting1
DB01073Fludarabine0Completed1
DB00688Mycophenolate mofetil0Completed1
DB12001Abemaciclib1Recruiting1
DB05812Abiraterone1Recruiting1
DB08916Afatinib1Recruiting1
DB00062Albumin human1Recruiting1
DB09495Avobenzone1Recruiting1
DB13915Axicabtagene ciloleucel1Not Yet Recruiting1
DB05015Belinostat1Recruiting1
DB00112Bevacizumab1Recruiting1
DB01128Bicalutamide1Recruiting1
DB09052Blinatumomab1Active Not Recruiting1
DB00188Bortezomib1Recruiting1
DB16741Bortezomib D-mannitol1Recruiting1
DB06772Cabazitaxel1Recruiting1
DB08875Cabozantinib1Recruiting1
DB01101Capecitabine1Recruiting1
DB00958Carboplatin1Recruiting1
DB08889Carfilzomib1Recruiting1
DB00482Celecoxib1Recruiting1
DB14006Choline salicylate1Recruiting1
DB05239Cobimetinib1Recruiting1
DB12483Copanlisib1Recruiting2
DB00531Cyclophosphamide1Active Not Recruiting1
DB00531Cyclophosphamide1Not Yet Recruiting2
DB00531Cyclophosphamide1Recruiting1
DB00531Cyclophosphamide1Terminated1
DB08912Dabrafenib1Recruiting1
DB11963Dacomitinib1Recruiting1
DB09331Daratumumab1Recruiting1
DB12941Darolutamide1Recruiting1
DB01254Dasatinib1Recruiting1
DB00694Daunorubicin1Recruiting1
DB00997Doxorubicin1Recruiting1
DB11714Durvalumab1Recruiting1
DB13874Enasidenib1Recruiting1
DB11986Entrectinib1Recruiting1
DB08899Enzalutamide1Recruiting1
DB00530Erlotinib1Recruiting1
DB01590Everolimus1Recruiting1
DB01073Fludarabine1Active Not Recruiting1
DB01073Fludarabine1Not Yet Recruiting2
DB01073Fludarabine1Recruiting1
DB01073Fludarabine1Terminated1
DB09502Fludeoxyglucose (18F)1Recruiting1
DB13134Fluorine F-181Recruiting1
DB00544Fluorouracil1Recruiting1
DB00441Gemcitabine1Recruiting1
DB09053Ibrutinib1Active Not Recruiting1
DB09054Idelalisib1Recruiting1
DB00619Imatinib1Recruiting1
DB06186Ipilimumab1Recruiting1
DB00480Lenalidomide1Active Not Recruiting2
DB09078Lenvatinib1Recruiting1
DB00650Leucovorin1Recruiting1
DB16222Loncastuximab tesirine1Recruiting1
DB12130Lorlatinib1Recruiting1
DB00678Losartan1Recruiting1
DB00888Mechlorethamine1Active Not Recruiting1
DB00688Mycophenolate mofetil1Active Not Recruiting1
DB00688Mycophenolate mofetil1Terminated1
DB15721Natural Killer Cell1Active Not Recruiting1
DB11828Neratinib1Recruiting1
DB09035Nivolumab1Recruiting2
DB08935Obinutuzumab1Recruiting1
DB09496Octinoxate1Recruiting1
DB09074Olaparib1Recruiting1
DB00526Oxaliplatin1Recruiting1
DB01229Paclitaxel1Recruiting1
DB09073Palbociclib1Recruiting1
DB06603Panobinostat1Recruiting1
DB09037Pembrolizumab1Recruiting2
DB06366Pertuzumab1Recruiting1
DB11759Pevonedistat1Active Not Recruiting1
DB08901Ponatinib1Recruiting1
DB08896Regorafenib1Recruiting1
DB00073Rituximab1Active Not Recruiting1
DB00073Rituximab1Recruiting1
DB06176Romidepsin1Recruiting1
DB08877Ruxolitinib1Recruiting1
DB11942Selinexor1Recruiting1
DB00877Sirolimus1Recruiting1
DB00877Sirolimus1Terminated1
DB00398Sorafenib1Recruiting1
DB01268Sunitinib1Recruiting1
DB00864Tacrolimus1Active Not Recruiting1
DB08911Trametinib1Recruiting1
DB00072Trastuzumab1Recruiting1
DB05773Trastuzumab emtansine1Recruiting1
DB00755Tretinoin1Recruiting1
DB08881Vemurafenib1Recruiting1
DB11581Venetoclax1Recruiting2
DB08828Vismodegib1Recruiting1
DB02546Vorinostat1Recruiting1
DB160479-ING-411 / 2Recruiting1
DB00062Albumin human1 / 2Recruiting1
DB00041Aldesleukin1 / 2Active Not Recruiting1
DB02379Beta-D-Glucose1 / 2Active Not Recruiting1
DB02379Beta-D-Glucose1 / 2Completed1
DB00188Bortezomib1 / 2Completed1
DB16741Bortezomib D-mannitol1 / 2Completed1
DB00958Carboplatin1 / 2Completed1
DB00958Carboplatin1 / 2Recruiting1
DB00262Carmustine1 / 2Active Not Recruiting1
DB00262Carmustine1 / 2Completed1
DB00531Cyclophosphamide1 / 2Active Not Recruiting1
DB00531Cyclophosphamide1 / 2Completed1
DB00531Cyclophosphamide1 / 2Not Yet Recruiting1
DB00531Cyclophosphamide1 / 2Recruiting1
DB00091Cyclosporine1 / 2Completed1
DB00987Cytarabine1 / 2Active Not Recruiting1
DB00987Cytarabine1 / 2Completed2
DB01234Dexamethasone1 / 2Completed2
DB00997Doxorubicin1 / 2Recruiting1
DB00773Etoposide1 / 2Active Not Recruiting1
DB00773Etoposide1 / 2Completed1
DB00099Filgrastim1 / 2Completed1
DB01073Fludarabine1 / 2Active Not Recruiting1
DB01073Fludarabine1 / 2Completed1
DB01073Fludarabine1 / 2Not Yet Recruiting1
DB01073Fludarabine1 / 2Recruiting1
DB00441Gemcitabine1 / 2Recruiting1
DB06186Ipilimumab1 / 2Active Not Recruiting1
DB00762Irinotecan1 / 2Recruiting1
DB01206Lomustine1 / 2Recruiting1
DB00888Mechlorethamine1 / 2Active Not Recruiting1
DB00888Mechlorethamine1 / 2Completed1
DB14123Menthol1 / 2Completed1
DB14123Menthol1 / 2Recruiting1
DB00688Mycophenolate mofetil1 / 2Completed1
DB15721Natural Killer Cell1 / 2Active Not Recruiting1
DB09035Nivolumab1 / 2Active Not Recruiting1
DB14844ONC-2011 / 2Terminated1
DB01229Paclitaxel1 / 2Recruiting1
DB00073Rituximab1 / 2Active Not Recruiting1
DB00073Rituximab1 / 2Completed2
DB00877Sirolimus1 / 2Completed1
DB06287Temsirolimus1 / 2Completed1
DB11581Venetoclax1 / 2Active Not Recruiting1
DB00026Anakinra2Recruiting1
DB09312Antilymphocyte immunoglobulin (horse)2Active Not Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)2Active Not Recruiting1
DB13915Axicabtagene ciloleucel2Recruiting1
DB00928Azacitidine2Not Yet Recruiting1
DB02379Beta-D-Glucose2Completed1
DB08870Brentuximab vedotin2Recruiting1
DB00262Carmustine2Completed1
DB00531Cyclophosphamide2Completed1
DB00531Cyclophosphamide2Recruiting1
DB00091Cyclosporine2Active Not Recruiting1
DB00987Cytarabine2Completed1
DB14860Ensartinib2Recruiting2
DB12147Erdafitinib2Recruiting1
DB12147Erdafitinib2Suspended1
DB00773Etoposide2Completed1
DB01073Fludarabine2Completed1
DB01073Fludarabine2Recruiting1
DB15127Hydrogen2Active Not Recruiting1
DB00078Ibritumomab tiuxetan2Active Not Recruiting1
DB00078Ibritumomab tiuxetan2Completed1
DB14568Ivosidenib2Recruiting1
DB14723Larotrectinib2Recruiting2
DB00888Mechlorethamine2Completed1
DB14123Menthol2Recruiting1
DB15434Mosunetuzumab2Not Yet Recruiting1
DB00688Mycophenolate mofetil2Active Not Recruiting1
DB00688Mycophenolate mofetil2Completed1
DB09035Nivolumab2Recruiting2
DB09074Olaparib2Active Not Recruiting1
DB09074Olaparib2Recruiting1
DB09073Palbociclib2Recruiting1
DB09073Palbociclib2Suspended1
DB09037Pembrolizumab2Recruiting1
DB12240Polatuzumab vedotin2Not Yet Recruiting1
DB00073Rituximab2Active Not Recruiting1
DB15685Selpercatinib2Recruiting2
DB11689Selumetinib2Active Not Recruiting1
DB11689Selumetinib2Recruiting1
DB14546Sulfate ion2Active Not Recruiting1
DB00864Tacrolimus2Completed1
DB12887Tazemetostat2Active Not Recruiting1
DB12887Tazemetostat2Recruiting1
DB04960Tipifarnib2Recruiting2
DB14922Tislelizumab2Recruiting1
DB13930Ulixertinib2Active Not Recruiting1
DB13930Ulixertinib2Recruiting1
DB08881Vemurafenib2Active Not Recruiting1
DB08881Vemurafenib2Recruiting1