Cutaneous T Cell Lymphomas (CTCL)

Also known as: Lymphoma, Cutaneous T-Cell / Cutaneous T Cell Lymphoma (CTCL) / Cutaneous T Cell Lymphoma / Cutaneous T-Cell Lymphoma (CTCL) / Cutaneous T-Cell Lymphoma / Cutaneous T-Cell Lymphomas / Lymphoma,T-cell Cutaneous / Lymphoma, T-Cell, Cutaneous / Cutaneous T-cell lymphoma (morphologic abnormality) / Primary cutaneous T-cell lymphoma (disorder) / Cutaneous lymphoma (disorder)

DrugDrug NameDrug Description
DB00242CladribineA purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs.
DB00004Denileukin diftitoxA recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 receptor.
DB00441GemcitabineA nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
DB00034Interferon alfa-2aA form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
DB00553MethoxsalenA furocoumarin used to treat psoriasis and vitiligo.
DB06813PralatrexateAn antineoplastic agent used for the treatment of relapsed or refractory peripheral T-cell lymphoma.
DB06176RomidepsinA histone deacetylase (HDAC) inhibitor used to treat cutaneous T-cell lymphoma.
DrugDrug NameTargetType
DB00242CladribinePurine nucleoside phosphorylasetarget
DB00242CladribineDNAtarget
DB00242CladribineDeoxycytidine kinaseenzyme
DB00242CladribineRibonucleoside-diphosphate reductase large subunittarget
DB00242CladribineRibonucleoside-diphosphate reductase subunit M2target
DB00242CladribineRibonucleoside-diphosphate reductase subunit M2 Btarget
DB00242CladribineDNA polymerase alpha catalytic subunittarget
DB00242CladribineDNA polymerase epsilon catalytic subunit Atarget
DB00242CladribineDNA polymerase epsilon subunit 2target
DB00242CladribineDNA polymerase epsilon subunit 3target
DB00242CladribineDNA polymerase epsilon subunit 4target
DB00242CladribineATP-binding cassette sub-family G member 2transporter
DB00242CladribineSolute carrier family 28 member 3transporter
DB00004Denileukin diftitoxInterleukin-2 receptor subunit alphatarget
DB00004Denileukin diftitoxCytokine receptor common subunit gammatarget
DB00004Denileukin diftitoxInterleukin-2 receptor subunit betatarget
DB00441GemcitabineRibonucleoside-diphosphate reductase large subunittarget
DB00441GemcitabineUMP-CMP kinasetarget
DB00441GemcitabineThymidylate synthasetarget
DB00441GemcitabineCytidine deaminaseenzyme
DB00441GemcitabineDeoxycytidine kinaseenzyme
DB00441GemcitabineP-glycoprotein 1transporter
DB00441GemcitabineMultidrug resistance-associated protein 7transporter
DB00441GemcitabineEquilibrative nucleoside transporter 1transporter
DB00441GemcitabineDNAtarget
DB00441GemcitabineSodium/nucleoside cotransporter 1transporter
DB00441GemcitabineEquilibrative nucleoside transporter 2transporter
DB00441GemcitabineSolute carrier family 28 member 3transporter
DB00441GemcitabineThymidine kinase 2, mitochondrialenzyme
DB00441GemcitabineUMP-CMP kinaseenzyme
DB00441GemcitabineNucleoside diphosphate kinase Aenzyme
DB00034Interferon alfa-2aInterferon alpha/beta receptor 1target
DB00034Interferon alfa-2aInterferon alpha/beta receptor 2target
DB00034Interferon alfa-2aCytochrome P450 1A2enzyme
DB00553MethoxsalenDNAtarget
DB00553MethoxsalenCytochrome P450 2A6enzyme
DB00553MethoxsalenCytochrome P450 1A2enzyme
DB00553MethoxsalenCytochrome P450 1A1enzyme
DB00553MethoxsalenCytochrome P450 2A13enzyme
DB06813PralatrexateDihydrofolate reductasetarget
DB06813PralatrexateThymidylate synthasetarget
DB06813PralatrexateFolate transporter 1transporter
DB06813PralatrexateCanalicular multispecific organic anion transporter 1transporter
DB06813PralatrexateATP-binding cassette sub-family G member 2transporter
DB06813PralatrexateSerum albumincarrier
DB06813PralatrexateFolylpolyglutamate synthase, mitochondrialtarget
DB06813PralatrexateProton-coupled folate transportertransporter
DB06813PralatrexateCanalicular multispecific organic anion transporter 2transporter
DB06813PralatrexateSolute carrier organic anion transporter family member 1B3transporter
DB06176RomidepsinCytochrome P450 3A4enzyme
DB06176RomidepsinCytochrome P450 3A5enzyme
DB06176RomidepsinP-glycoprotein 1transporter
DB06176RomidepsinSolute carrier organic anion transporter family member 1B3transporter
DB06176RomidepsinCytochrome P450 1A1enzyme
DB06176RomidepsinCytochrome P450 2B6enzyme
DB06176RomidepsinCytochrome P450 2C19enzyme
DB06176RomidepsinHistone deacetylase 1target
DB06176RomidepsinHistone deacetylase 2target
DB06176RomidepsinHistone deacetylase 4target
DB06176RomidepsinHistone deacetylase 6target
DB06176RomidepsinMultidrug resistance-associated protein 1target
DB06176RomidepsinBile salt export pumptransporter
DB06176RomidepsinSolute carrier organic anion transporter family member 1B1transporter
DB06176RomidepsinSolute carrier family 22 member 6transporter
DB06176RomidepsinSolute carrier family 22 member 2transporter
DB06176RomidepsinHistone deacetylasetarget
DrugDrug NamePhaseStatusCount
DB00254Doxycycline0Recruiting1
DB11714Durvalumab0Withdrawn1
DB00724Imiquimod0Recruiting1
DB00087Alemtuzumab1Completed1
DB00098Antithymocyte immunoglobulin (rabbit)1Recruiting1
DB06769Bendamustine1Recruiting1
DB00307Bexarotene1Completed1
DB00307Bexarotene1Recruiting1
DB08870Brentuximab vedotin1Completed1
DB08870Brentuximab vedotin1Not Yet Recruiting1
DB08870Brentuximab vedotin1Recruiting1
DB01008Busulfan1Recruiting1
DB01101Capecitabine1Recruiting1
DB14931Cobomarsen1Completed1
DB01234Dexamethasone1Completed1
DB01234Dexamethasone1Recruiting1
DB00997Doxorubicin1Recruiting1
DB05076Fenretinide1Not Yet Recruiting1
DB01073Fludarabine1Recruiting2
DB00441Gemcitabine1Completed1
DB15322Lacutamab1Completed1
DB00480Lenalidomide1Completed1
DB00480Lenalidomide1Recruiting1
DB12498Mogamulizumab1Not Yet Recruiting1
DB00526Oxaliplatin1Completed1
DB11697Pacritinib1Terminated1
DB06603Panobinostat1Completed1
DB00019Pegfilgrastim1Completed1
DB09037Pembrolizumab1Withdrawn1
DB05527Pralatrexate1Completed1
DB06813Pralatrexate1Completed2
DB14869Remetinostat1Completed1
DB12392Resminostat1Completed1
DB06176Romidepsin1Completed1
DB06176Romidepsin1Recruiting3
DB06176Romidepsin1Terminated2
DB15147Tinostamustine1Recruiting1
DB13076Yttrium Y-901Completed1
DB00307Bexarotene1 / 2Completed1
DB00531Cyclophosphamide1 / 2Completed1
DB00997Doxorubicin1 / 2Completed1
DB11714Durvalumab1 / 2Completed1
DB01590Everolimus1 / 2Completed1
DB00860Prednisolone1 / 2Completed1
DB06530Resiquimod1 / 2Completed1
DB05471SGN-301 / 2Completed1
DB00799Tazarotene1 / 2Unknown Status1
DB11771Tremelimumab1 / 2Completed1
DB00541Vincristine1 / 2Completed1
DB02546Vorinostat1 / 2Terminated1
DB16307A-dmDT390-bisFv(UCHT1)2Completed1
DB11595Atezolizumab2Active Not Recruiting1
DB05015Belinostat2Terminated1
DB00307Bexarotene2Completed1
DB08870Brentuximab vedotin2Completed1
DB11672Curcumin2Withdrawn1
DB00091Cyclosporine2Active Not Recruiting1
DB12731Daporinad2Completed1
DB00254Doxycycline2Terminated1
DB06486Enzastaurin2Completed1
DB01590Everolimus2Terminated1
DB06185Forodesine2Completed1
DB15322Lacutamab2Recruiting1
DB00480Lenalidomide2Unknown Status1
DB00888Mechlorethamine2Completed1
DB00888Mechlorethamine2Unknown Status1
DB00553Methoxsalen2Withdrawn1
DB12498Mogamulizumab2Completed1
DB06603Panobinostat2Completed1
DB06603Panobinostat2Terminated2
DB09037Pembrolizumab2Recruiting1
DB00552Pentostatin2Completed1
DB12985Quisinostat2Completed1
DB14869Remetinostat2Unknown Status1
DB12392Resminostat2Active Not Recruiting1
DB06176Romidepsin2Completed2
DB00412Rosiglitazone2Completed1
DB06365Sapacitabine2Terminated1
DB11942Selinexor2Terminated1
DB15765Sintilimab2Recruiting1
DB00877Sirolimus2Withdrawn1
DB14922Tislelizumab2Completed1
DB00620Triamcinolone2Completed1
DB06334Tucidinostat2Recruiting1
DB14276Turmeric2Withdrawn1
DB02546Vorinostat2Completed1
DB00307Bexarotene3Completed1
DB08870Brentuximab vedotin3Completed1
DB13014Hypericin3Completed1
DB00563Methotrexate3Completed1
DB12498Mogamulizumab3Completed1
DB01183Naloxone3Recruiting1
DB02546Vorinostat3Completed1
DB00628Clorazepic acid4Terminated1
DB00004Denileukin diftitox4Completed3
DB00105Interferon alfa-2b4Terminated1
DB00563Methotrexate4Terminated1
DB00553Methoxsalen4Completed1
DB00307BexaroteneNot AvailableNot Yet Recruiting1
DB08870Brentuximab vedotinNot AvailableNo Longer Available1
DB00004Denileukin diftitoxNot AvailableRecruiting1
DB00888MechlorethamineNot AvailableNot Yet Recruiting1
DB06176RomidepsinNot AvailableCompleted1
DB00620TriamcinoloneNot AvailableNot Yet Recruiting1
DB02546VorinostatNot AvailableNo Longer Available1