Pharmaco-transcriptomicsUp/down regulation of genes due to the metabolism of pharmaceutical compounds

Pharmaco-genomics Pharmaco-metabolomics Pharmaco-transcriptomics Pharmaco-proteomics Search

Displaying entries 74301 - 74325 of 102031 in total

Drug	Drug Groups	Gene	Gene ID	Change	Interaction	Chromosome	References
							Clear
Simvastatin	Approved Investigational	CDT1	81620	downregulated	Simvastatin results in decreased expression of CDT1 mRNA	16q24.3	A24239
Simvastatin	Approved Investigational	COL1A1	1277	downregulated	Simvastatin results in decreased expression of COL1A1 mRNA	17q21.33	A24262
Simvastatin	Approved Investigational	COL1A1	1277	upregulated	Simvastatin results in increased expression of COL1A1 mRNA	17q21.33	A20969
Simvastatin	Approved Investigational	COL3A1	1281	upregulated	Simvastatin results in increased expression of COL3A1 mRNA	2q32.2	A24241
Simvastatin	Approved Investigational	COL7A1	1294	upregulated	Simvastatin results in increased expression of COL7A1 mRNA	3p21.31	A24239
Simvastatin	Approved Investigational	CTLA4	1493	downregulated	Simvastatin results in decreased expression of CTLA4 mRNA	2q33.2	A24260
Simvastatin	Approved Investigational	CTNNAL1	8727	downregulated	Simvastatin results in decreased expression of CTNNAL1 mRNA	9q31.3	A24239
Simvastatin	Approved Investigational	CX3CR1	1524	downregulated	Simvastatin results in decreased expression of CX3CR1 mRNA	3p22.2	A24264
Simvastatin	Approved Investigational	CXCL8	3576	downregulated	Simvastatin results in decreased expression of CXCL8 mRNA	4q13.3	A20970
Simvastatin	Approved Investigational	CYP2B6	1555	upregulated	Simvastatin results in increased expression of CYP2B6 mRNA	19q13.2	A20971
Simvastatin	Approved Investigational	CYP3A4	1576	upregulated	[Simvastatin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA	7q22.1	A21544
Simvastatin	Approved Investigational	CYP3A4	1576	upregulated	Simvastatin results in increased expression of CYP3A4 mRNA	7q22.1	A21238
Simvastatin	Approved Investigational	CYR61	3491	downregulated	Simvastatin results in decreased expression of CYR61 mRNA	1p22.3	A24239
Simvastatin	Approved Investigational	DBF4	10926	downregulated	Simvastatin results in decreased expression of DBF4 mRNA	7q21.12	A24239
Simvastatin	Approved Investigational	DSPP	1834	upregulated	Simvastatin results in increased expression of DSPP mRNA	4q22.1	A24251
Simvastatin	Approved Investigational	E2F1	1869	downregulated	Simvastatin results in decreased expression of E2F1 mRNA	20q11.22	A24239
Simvastatin	Approved Investigational	EDN1	1906	downregulated	Simvastatin results in decreased expression of EDN1 mRNA	6p24.1	A24265
Simvastatin	Approved Investigational	F3	2152	downregulated	Simvastatin results in decreased expression of F3 mRNA	1p21.3	A24266 A24267 A24240
Simvastatin	Approved Investigational	F3	2152	upregulated	Simvastatin results in increased expression of F3 mRNA	1p21.3	A24268
Simvastatin	Approved Investigational	FASN	2194	upregulated	Simvastatin results in increased expression of FASN mRNA	17q25.3	A20972
Simvastatin	Approved Investigational	FDFT1	2222	upregulated	Simvastatin results in increased expression of FDFT1 mRNA	8p23.1	A23952
Simvastatin	Approved Investigational	FDPS	2224	upregulated	Simvastatin results in increased expression of FDPS mRNA	1q22	A23952
Simvastatin	Approved Investigational	FOS	2353	downregulated	Simvastatin results in decreased expression of FOS mRNA	14q24.3	A24269
Simvastatin	Approved Investigational	GJB2	2706	upregulated	Simvastatin results in increased expression of GJB2 mRNA	13q12.11	A24239
Simvastatin	Approved Investigational	HMGCR	3156	upregulated	Simvastatin results in increased expression of HMGCR mRNA	5q13.3	A20973 A24270 A24271 A24233 A23952 A23129 A20975

Displaying entries 74301 - 74325 of 102031 in total

Pharmaco-transcriptomicsUp/down regulation of genes due to the metabolism of pharmaceutical compounds

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