Gaba-gated chloride channel, putative

Details

Name

Gaba-gated chloride channel, putative

Synonyms

Not Available

Gene Name

8239847

Organism

Pediculus humanus subsp. corporis

Amino acid sequence

>lcl|BSEQ0052862|Gaba-gated chloride channel, putative
MVRSMGPISEIDMTYSMDLYFRQSWIDKRLAFKGNKETLALSITMLEKIWKPDTYFYNGK
QSYLHTITTPNKFVRLYQDGRVLYSSRLTIKAGCPMNLENFPMDTQRCPLKFGSFGYTTN
DVVYKWNSQRQIVIAEDMKLSQFDLIANISANETDKVNIVHSRVYTIKYSMLLVSFHLQR
HMGNFLIQVYGPCILLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVP
YPTALDFFVFLSFAFIFATIIQFAVVHYFTKYGSGECYFGMDLSSESDSNSIPFERSIKL
RSSDSSQNSKTEFKIDDVSSRVQKQSGDDDEKYHGKRKNNKTGISGNAITQNFHSFNSPG
SSSSLNNVNGKKRRRKRRIPRYNSVSKIDKMSRIVFPMLFAAINVLYWYSYLIRSERIHS
KNK

Number of residues

423

Molecular Weight

48851.68

Theoretical pI

Not Available

GO Classification

Functions

chloride channel activity / extracellular ligand-gated monoatomic ion channel activity / GABA-A receptor activity

Components

plasma membrane

General Function

Not Available

Specific Function

Chloride channel activity

Pfam Domain Function

• Neur_chan_LBD (PF02931)
• Neur_chan_memb (PF02932)

Transmembrane Regions

185-203 215-232 244-269 394-413

Cellular Location

Membrane

Gene sequence

>lcl|BSEQ0052863|Gaba-gated chloride channel, putative (8239847)
ATGGTACGAAGCATGGGCCCGATTTCGGAAATTGATATGACTTATTCGATGGATCTTTAT
TTTAGACAATCTTGGATTGATAAAAGGTTAGCGTTCAAAGGAAACAAGGAAACTTTGGCG
TTGAGCATAACAATGTTGGAGAAAATATGGAAACCGGATACGTATTTTTACAACGGTAAA
CAATCTTATCTCCACACGATAACGACTCCGAATAAATTCGTTAGACTTTATCAAGATGGA
CGAGTTCTTTATTCCAGCAGGCTCACGATAAAAGCCGGTTGTCCGATGAATTTGGAAAAT
TTTCCAATGGACACGCAAAGATGTCCGTTAAAATTTGGAAGTTTTGGTTACACGACAAAC
GACGTGGTTTACAAATGGAATTCGCAACGGCAAATCGTCATAGCAGAAGACATGAAATTA
TCACAATTCGATTTGATAGCAAATATATCCGCTAACGAAACGGATAAAGTTAACATTGTA
CATTCGAGAGTTTACACCATAAAATATTCAATGTTACTCGTTAGTTTTCACCTACAGAGA
CACATGGGTAATTTTCTAATACAAGTTTACGGTCCTTGCATTCTATTGGTCGTTTTGTCT
TGGGTCTCGTTTTGGCTCAATAGAGAAGCAACAGCCGACAGAGTATCATTGGGTATAACA
ACGGTTTTAACGATGACGTTTTTGGGTTTGGAAGCAAGAACGGACCTTCCAAAAGTACCT
TATCCGACAGCTTTAGATTTTTTCGTTTTCCTTTCGTTCGCTTTTATATTTGCGACAATC
ATTCAGTTTGCCGTCGTTCATTATTTTACAAAATACGGTTCGGGTGAATGTTATTTCGGA
ATGGATTTAAGTTCAGAATCAGACTCGAATTCGATACCATTCGAAAGAAGCATCAAATTG
AGAAGTTCGGATTCGAGTCAAAATTCTAAAACCGAATTTAAAATCGATGACGTTTCATCG
CGAGTACAAAAACAATCCGGAGACGATGATGAAAAATATCACGGGAAACGTAAAAATAAT
AAAACTGGAATTTCCGGAAATGCAATAACTCAAAATTTTCATAGTTTTAATTCTCCCGGA
AGTAGTAGTAGTTTAAATAACGTAAATGGTAAAAAACGACGACGTAAAAGAAGAATACCG
CGTTATAATTCCGTTAGTAAAATCGATAAAATGAGTCGTATTGTTTTCCCTATGTTATTT
GCCGCCATTAATGTTTTGTATTGGTATAGTTATTTAATTAGAAGCGAAAGAATACATAGT
AAAAATAAATAA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	E0W492
UniProtKB Entry Name	E0W492_PEDHC

General References

Not Available

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB17992	Lotilaner	approved, vet_approved	unknown	antagonist	Details