Probable thiol peroxidase
Details
- Name
- Probable thiol peroxidase
- Synonyms
- 1.11.1.-
- Gene Name
- tpx
- Organism
- Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
- Amino acid sequence
>lcl|BSEQ0051207|Probable thiol peroxidase MAQITLRGNAINTVGELPAVGSPAPAFTLTGGDLGVISSDQFRGKSVLLNIFPSVDTPVC ATSVRTFDERAAASGATVLCVSKDLPFAQKRFCGAEGTENVMPASAFRDSFGEDYGVTIA DGPMAGLLARAIVVIGADGNVAYTELVPEIAQEPNYEAALAALGA
- Number of residues
- 165
- Molecular Weight
- 16895.94
- Theoretical pI
- Not Available
- GO Classification
- Functionsdisulfide oxidoreductase activity / peroxidase activity / peroxiredoxin activity / thioredoxin peroxidase activityProcessescell redox homeostasis / evasion or tolerance by symbiont of host-produced nitric oxide / oxidation-reduction process / pathogenesis / response to nitrosative stress / response to oxidative stressComponentscell wall / cytosol / extracellular region
- General Function
- Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity).
- Specific Function
- Disulfide oxidoreductase activity
- Pfam Domain Function
- Redoxin (PF08534)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0051208|Probable thiol peroxidase (tpx) ATGGCACAGATAACCCTGCGAGGAAACGCGATCAATACCGTCGGTGAGCTACCTGCTGTC GGATCCCCGGCCCCGGCCTTCACCCTGACCGGGGGCGATCTGGGGGTGATCAGCAGCGAC CAGTTCCGGGGTAAGTCCGTGTTGCTGAACATCTTTCCATCCGTGGACACACCGGTGTGC GCGACGAGTGTGCGAACCTTCGACGAGCGTGCGGCGGCAAGTGGCGCTACCGTGCTGTGT GTCTCGAAGGATCTGCCGTTCGCCCAGAAGCGCTTCTGCGGCGCCGAGGGCACCGAAAAC GTCATGCCCGCGTCGGCATTCCGGGACAGCTTCGGCGAGGATTACGGCGTGACCATCGCC GACGGGCCGATGGCCGGGCTGCTCGCCCGCGCAATCGTGGTGATCGGCGCGGACGGCAAC GTCGCCTACACGGAATTGGTGCCGGAAATCGCGCAAGAACCCAACTACGAAGCGGCGCTG GCCGCGCTGGGCGCCTAG
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P9WG35 UniProtKB Entry Name TPX_MYCTU - General References
- Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE 3rd, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares S, Sulston JE, Taylor K, Whitehead S, Barrell BG: Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature. 1998 Jun 11;393(6685):537-44. [Article]
- Kelkar DS, Kumar D, Kumar P, Balakrishnan L, Muthusamy B, Yadav AK, Shrivastava P, Marimuthu A, Anand S, Sundaram H, Kingsbury R, Harsha HC, Nair B, Prasad TS, Chauhan DS, Katoch K, Katoch VM, Kumar P, Chaerkady R, Ramachandran S, Dash D, Pandey A: Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry. Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3. [Article]