Insulin-like growth factor-binding protein 7
Details
- Name
- Insulin-like growth factor-binding protein 7
- Synonyms
- IBP-7
- IGFBP-rP1
- MAC25
- MAC25 protein
- PGI2-stimulating factor
- Prostacyclin-stimulating factor
- PSF
- TAF
- Tumor-derived adhesion factor
- Gene Name
- IGFBP7
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0004170|Insulin-like growth factor-binding protein 7 MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCC PMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVC GSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK EDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL
- Number of residues
- 282
- Molecular Weight
- 29130.055
- Theoretical pI
- 7.94
- GO Classification
- Processescell adhesion / negative regulation of cell proliferation / regulation of cell growthComponentsextracellular exosome / extracellular region / extracellular space
- General Function
- Not Available
- Specific Function
- Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Secreted
- Gene sequence
>lcl|BSEQ0011540|Insulin-like growth factor-binding protein 7 (IGFBP7) ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTC CTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGC CCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTAC TGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCA GCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCC GAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCT TCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGTAAAAAGGGGTCAC TATGGAGTTCAAAGGACAGAACTCCTGCCTGGTGACCGGGACAACCTGGCCATTCAGACC CGGGGTGGCCCAGAAAAGCATGAAGTAACTGGCTGGGTGCTGGTATCTCCTCTAAGTAAG GAAGATGCTGGAGAATATGAGTGCCATGCATCCAATTCCCAAGGACAGGCTTCAGCATCA GCAAAAATTACAGTGGTTGATGCCTTACATGAAATACCAGTGAAAAAAGGTACACAATAA
- Chromosome Location
- 4
- Locus
- 4q12
- External Identifiers
Resource Link UniProtKB ID Q16270 UniProtKB Entry Name IBP7_HUMAN GenBank Protein ID 307151 GenBank Gene ID L19182 GenAtlas ID IGFBP7 HGNC ID HGNC:5476 - General References
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