Nitrous-oxide reductase
Details
- Name
- Nitrous-oxide reductase
- Synonyms
- 1.7.2.4
- N(2)OR
- N2O reductase
- Gene Name
- nosZ
- UniProtKB Entry
- Q51705Swiss-Prot
- Organism
- Paracoccus denitrificans
- NCBI Taxonomy ID
- 266
- Amino acid sequence
>lcl|BSEQ0012098|Nitrous-oxide reductase MESKQEKGLSRRALLGATAGGAAVAGAFGGRLALGPAALGLGTAGVATVAGSGAALAASG DGSVAPGQLDDYYGFWSSGQSGEMRILGIPSMRELMRVPVFNRCSATGWGQTNESVRIHE RTMSERTKKFLAANGKRIHDNGDLHHVHMSFTEGKYDGRFLFMNDKANTRVARVRCDVMK CDAILEIPNAKGIHGLRPQKWPRSNYVFCNGEDETPLVNDGTNMEDVANYVNVFTAVDAD KWEVAWQVLVSGNLDNCDADYEGKWAFSTSYNSEKGMTLPEMTAAEMDHIVVFNIAEIEK AIAAGDYQELNGVKVVDGRKEASSLFTRYIPIANNPHGCNMAPDKKHLCVAGKLSPTATV LDVTRFDAVFYENADPRSAVVAEPELGLGPLHTAFDGRGNAYTSLFLDSQVVKWNIEDAI RAYAGEKVDPIKDKLDVHYQPGHLKTVMGETLDATNDWLVCLSKFSKDRFLNVGPLKPEN DQLIDISGDKMVLVHDGPTFAEPHDAIAVHPSILSDIKSVWDRNDPMWAETRAQAEADGV DIDNWTEEVIRDGNKVRVYMSSVAPSFSIESFTVKEGDEVTVIVTNLDEIDDLTHGFTMG NYGVAMEIGPQMTSSVTFVAANPGVYWYYCQWFCHALHMEMRGRMLVEPKEA
- Number of residues
- 652
- Molecular Weight
- 71412.995
- Theoretical pI
- 4.88
- GO Classification
- Functionscalcium ion binding / copper ion binding / cytochrome-c oxidase activity / nitrous-oxide reductase activityProcessesdenitrification pathwayComponentsmembrane / periplasmic space
- General Function
- Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
- Specific Function
- calcium ion binding
- Pfam Domain Function
- Cupredoxin_1 (PF13473)
- Signal Regions
- 1-57
- Transmembrane Regions
- Not Available
- Cellular Location
- Periplasm
- Gene sequence
>lcl|BSEQ0005847|1959 bp ATGGAATCGAAACAGGAAAAGGGTCTCAGCCGCCGCGCGCTTTTGGGCGCGACAGCCGGG GGCGCGGCCGTGGCCGGCGCGTTCGGCGGACGGCTGGCGCTGGGGCCGGCGGCGCTCGGC CTGGGCACGGCGGGGGTCGCGACCGTCGCCGGCAGTGGTGCGGCGCTGGCCGCCAGCGGC GACGGCTCGGTCGCGCCGGGGCAACTGGACGACTACTACGGCTTCTGGTCCTCGGGCCAG AGCGGCGAGATGCGCATCCTTGGCATTCCCTCGATGCGCGAGCTGATGCGGGTTCCGGTC TTCAACCGCTGCTCGGCCACCGGCTGGGGCCAGACCAACGAATCCGTGCGCATCCATGAG CGCACCATGAGCGAGCGGACGAAGAAGTTCCTTGCCGCCAATGGCAAGCGCATCCACGAC AACGGCGACCTGCACCACGTCCACATGTCCTTTACCGAGGGCAAATATGACGGCCGCTTC CTGTTCATGAACGACAAGGCCAATACCCGCGTGGCGCGGGTGCGCTGCGACGTGATGAAA TGCGACGCCATCCTGGAGATCCCCAACGCCAAGGGCATCCACGGCCTGCGGCCGCAGAAA TGGCCGCGCAGCAACTATGTCTTCTGCAATGGCGAGGACGAGACGCCGCTGGTCAACGAC GGCACCAACATGGAGGACGTGGCGAATTACGTGAACGTCTTCACCGCCGTCGATGCCGAC AAGTGGGAGGTCGCCTGGCAGGTGCTCGTCTCGGGCAACCTGGACAACTGCGATGCCGAT TACGAGGGCAAATGGGCCTTTTCGACCTCCTACAACTCGGAAAAGGGGATGACCCTGCCC GAGATGACGGCGGCCGAGATGGACCATATCGTCGTCTTCAACATCGCCGAGATCGAAAAG GCCATCGCTGCCGGCGACTATCAGGAACTGAACGGCGTCAAGGTCGTGGATGGCCGGAAA GAGGCAAGCAGCCTGTTCACCCGCTATATCCCCATCGCCAACAACCCGCATGGCTGCAAC ATGGCGCCGGACAAGAAGCACCTGTGCGTCGCGGGCAAGCTGTCGCCCACGGCGACGGTG CTGGACGTGACCCGGTTCGACGCGGTGTTCTATGAGAACGCCGATCCGCGCAGCGCCGTG GTGGCCGAGCCGGAACTGGGCCTTGGCCCGCTGCACACCGCCTTCGACGGGCGCGGCAAC GCCTATACCTCGCTATTCCTCGACAGCCAGGTGGTCAAGTGGAACATCGAGGATGCCATC CGCGCCTATGCCGGCGAGAAGGTCGACCCGATCAAGGACAAGCTGGACGTGCATTACCAG CCCGGCCACCTCAAGACCGTGATGGGCGAGACGCTGGACGCCACCAACGACTGGCTGGTC TGCCTGTCCAAGTTCTCGAAGGACCGCTTCCTGAACGTCGGGCCGCTGAAGCCGGAGAAC GACCAGCTGATCGACATCTCGGGCGACAAGATGGTGCTGGTCCATGACGGCCCCACCTTT GCCGAGCCGCACGACGCCATCGCCGTGCACCCCTCGATCCTGTCCGACATCAAGTCGGTC TGGGACCGCAACGACCCGATGTGGGCCGAGACCCGCGCTCAGGCCGAGGCCGATGGCGTC GACATCGACAACTGGACCGAAGAGGTGATCCGCGACGGCAACAAGGTGCGGGTCTACATG TCCAGCGTGGCGCCGAGCTTCTCGATCGAGAGCTTTACCGTCAAGGAGGGCGACGAGGTC ACGGTGATCGTCACCAACCTGGACGAGATCGACGATCTGACGCATGGCTTCACCATGGGC AACTACGGCGTCGCCATGGAGATCGGGCCGCAGATGACCAGCTCGGTCACCTTCGTCGCC GCCAATCCCGGGGTCTATTGGTATTATTGCCAATGGTTCTGCCATGCGCTGCACATGGAG ATGCGCGGCCGCATGCTGGTCGAGCCGAAGGAGGCCTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q51705 UniProtKB Entry Name NOSZ_PARDE GenBank Gene ID X74792 PDB ID(s) 1FWX - General References
- Hoeren FU, Berks BC, Ferguson SJ, McCarthy JE: Sequence and expression of the gene encoding the respiratory nitrous-oxide reductase from Paracoccus denitrificans. New and conserved structural and regulatory motifs. Eur J Biochem. 1993 Nov 15;218(1):49-57. [Article]
- Saunders NF, Hornberg JJ, Reijnders WN, Westerhoff HV, de Vries S, van Spanning RJ: The NosX and NirX proteins of Paracoccus denitrificans are functional homologues: their role in maturation of nitrous oxide reductase. J Bacteriol. 2000 Sep;182(18):5211-7. [Article]
- Haltia T, Brown K, Tegoni M, Cambillau C, Saraste M, Mattila K, Djinovic-Carugo K: Crystal structure of nitrous oxide reductase from Paracoccus denitrificans at 1.6 A resolution. Biochem J. 2003 Jan 1;369(Pt 1):77-88. [Article]
Associated Data
- Bio-Entities
Bio-Entity Type Nitrous-oxide reductase (Paracoccus denitrificans) protein primary- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details mu4-sulfido-quadro-tetracopper experimental unknown target Details