Purine nucleoside phosphorylase
Details
- Name
- Purine nucleoside phosphorylase
- Synonyms
- Not Available
- Gene Name
- Not Available
- UniProtKB Entry
- Q5SID9TrEMBL
- Organism
- Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
- NCBI Taxonomy ID
- 300852
- Amino acid sequence
>lcl|BSEQ0022310|Purine nucleoside phosphorylase MSPIHVRAHPGDVAERVLLPGDPGRAEWIAKTFLQNPRRYNDHRGLWGYTGLYKGVPVSV QTTGMGTPSAAIVVEELVRLGARVLVRVGTAGAASSDLAPGELIVAQGAVPLDGTTRQYL EGRPYAPVPDPEVFRALWRRAEALGYPHRVGLVASEDAFYATTPEEARAWARYGVLAFEM EASALFLLGRMRGVRTGAILAVSNRIGDPELAPPEVLQEGVRRMVEVALEAVLEV
- Number of residues
- 235
- Molecular Weight
- 25414.93
- Theoretical pI
- 6.53
- GO Classification
- Functionstransferase activity, transferring pentosyl groupsProcessesnucleoside metabolic process
- General Function
- Transferase activity, transferring pentosyl groups
- Specific Function
- Not Available
- Pfam Domain Function
- PNP_UDP_1 (PF01048)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0022311|Purine nucleoside phosphorylase ATGAGCCCCATCCACGTGCGCGCCCACCCCGGGGACGTGGCGGAGCGCGTCCTTCTTCCC GGGGATCCGGGCCGGGCCGAGTGGATCGCCAAGACCTTTTTGCAAAACCCCAGGCGGTAC AACGACCACCGGGGGCTTTGGGGGTACACGGGCCTTTACAAGGGCGTGCCCGTCTCCGTC CAGACCACGGGGATGGGCACCCCCTCGGCGGCCATCGTGGTGGAGGAGCTGGTCCGGCTT GGCGCCCGGGTCCTCGTCCGGGTGGGGACGGCGGGGGCCGCTTCTTCGGACCTCGCCCCG GGGGAGCTCATCGTGGCCCAGGGGGCCGTGCCCTTGGACGGCACCACCCGGCAGTACCTG GAGGGGCGCCCCTACGCCCCGGTGCCCGACCCCGAGGTCTTCCGGGCCCTCTGGCGCCGG GCGGAGGCCTTGGGCTACCCCCACCGGGTGGGGCTCGTGGCCAGCGAGGACGCCTTCTAC GCCACCACCCCCGAGGAGGCCCGGGCCTGGGCCCGCTACGGCGTCCTCGCCTTTGAGATG GAGGCCAGCGCCCTCTTCCTCCTCGGAAGGATGCGGGGGGTGCGGACGGGGGCCATCCTG GCCGTCTCCAACCGCATCGGCGATCCGGAGCTCGCTCCCCCTGAGGTGCTCCAAGAGGGC GTTCGGCGTATGGTGGAGGTGGCCCTCGAGGCCGTCCTGGAGGTTTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q5SID9 UniProtKB Entry Name Q5SID9_THET8 GenBank Gene ID AP008226 PDB ID(s) 1ODI, 1ODJ, 1ODK, 1ODL KEGG ID ttj:TTHA1435 NCBI Gene ID 3170145 - General References
- Tahirov TH, Inagaki E, Ohshima N, Kitao T, Kuroishi C, Ukita Y, Takio K, Kobayashi M, Kuramitsu S, Yokoyama S, Miyano M: Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus. J Mol Biol. 2004 Apr 9;337(5):1149-60. [Article]
Associated Data
- Bio-Entities
Bio-Entity Type Purine nucleoside phosphorylase (Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)) protein primary- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Guanosine experimental, investigational unknown target Details