Phosphodiesterase isozyme 4

Details

Name

Phosphodiesterase isozyme 4

Synonyms

Not Available

Gene Name

PDE4

Organism

Humans

Amino acid sequence

>lcl|BSEQ0052056|Phosphodiesterase isozyme 4
MVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGD
RERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL

Number of residues

102

Molecular Weight

11946.535

Theoretical pI

Not Available

GO Classification

Functions

3',5'-cyclic-nucleotide phosphodiesterase activity

Processes

signal transduction

General Function

Not Available

Specific Function

3',5'-cyclic-nucleotide phosphodiesterase activity

Pfam Domain Function

• PDEase_I (PF00233)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	Q86V67
UniProtKB Entry Name	Q86V67_HUMAN

General References

1. Zhou L, Thompson WJ, Potter DE: Multiple cyclic nucleotide phosphodiesterases in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 1999 Jul;40(8):1745-52. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB05676	Apremilast	approved, investigational	yes	antagonist	Details