Protein-glutamine gamma-glutamyltransferase Z
Details
- Name
- Protein-glutamine gamma-glutamyltransferase Z
- Synonyms
- TG(Z)
- TGase Z
- TGase-7
- TGZ
- Transglutaminase Z
- Transglutaminase-7
- Gene Name
- TGM7
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0016726|Protein-glutamine gamma-glutamyltransferase Z MDQVATLRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSFSRPFQSQNDHITF VAETGPKPSELLGTRATFFLTRVQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKI EISQGQGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSW PWNYGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQ GNWGEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVV SNFRSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGWQVL DPTPQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQEILAH NTSSIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFLDLL ESGGLRDQPAQLQLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALLHGG GTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVSGIAEVEETGRSMLVL KDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQIAKDLG TLVAGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFVTVAGAP
- Number of residues
- 710
- Molecular Weight
- 79940.615
- Theoretical pI
- 7.0
- GO Classification
- Functionsmetal ion binding / protein-glutamine gamma-glutamyltransferase activityProcessespeptide cross-linking
- General Function
- Protein-glutamine gamma-glutamyltransferase activity
- Specific Function
- Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0016727|Protein-glutamine gamma-glutamyltransferase Z (TGM7) ATGGATCAGGTGGCAACCTTGCGGCTTGAGTCTGTCGACCTGCAGAGCTCCAGGAACAAC AAGGAGCACCACACGCAGGAGATGGGCGTCAAGCGGCTCACTGTGCGCCGCGGCCAGCCC TTCTACCTCCGGCTGAGCTTCAGCCGACCCTTCCAGTCCCAGAACGACCACATCACCTTT GTGGCTGAGACCGGACCCAAGCCGTCAGAGCTGCTGGGGACCCGAGCCACATTCTTCCTC ACCCGGGTCCAGCCCGGGAATGTCTGGAGCGCTTCTGATTTCACCATTGACTCCAACTCT CTCCAAGTTTCCCTTTTCACACCAGCCAATGCAGTTATTGGCCATTACACTCTGAAAATA GAGATCTCTCAGGGCCAAGGTCACAGTGTGACTTACCCGCTGGGAACTTTCATCCTACTT TTTAACCCTTGGAGTCCAGAGGACGACGTCTACCTGCCAAGTGAAATACTGCTGCAGGAG TATATCATGCGAGATTATGGCTTTGTTTACAAGGGTCATGAAAGATTCATCACCTCCTGG CCCTGGAACTACGGGCAGTTTGAAGAGGACATCATAGACATCTGCTTTGAGATCCTGAAC AAGAGCCTGTATCACTTAAAGAACCCGGCCAAAGACTGTTCCCAGCGGAACGACGTGGTG TATGTGTGCAGGGTGGTGAGTGCCATGATCAACAGCAACGATGACAATGGCGTGCTGCAG GGGAACTGGGGCGAGGACTACTCCAAAGGGGTCAGTCCTCTGGAGTGGAAGGGCAGTGTG GCCATCCTACAGCAGTGGTCAGCCAGGGGCGGGCAGCCTGTGAAGTACGGACAGTGCTGG GTCTTCGCCTCTGTTATGTGCACCGTAATGAGATGCTTAGGTGTTCCAACCCGTGTTGTT TCCAATTTCCGTTCCGCGCACAACGTGGATAGGAACTTGACCATCGATACGTACTATGAC CGAAATGCCGAGATGCTGTCAACTCAGAAACGAGACAAAATATGGAACTTCCACGTCTGG AATGAGTGCTGGATGATCCGGAAAGATCTCCCACCAGGATACAACGGGTGGCAGGTTCTG GACCCCACTCCCCAGCAGACCAGCAGTGGGCTGTTCTGCTGTGGCCCTGCCTCTGTGAAG GCCATCAGGGAAGGGGATGTCCACCTGGCCTATGACACCCCTTTTGTGTATGCCGAGGTG AACGCCGATGAAGTCATTTGGCTCCTTGGGGATGGCCAGGCCCAGGAAATCCTGGCCCAC AACACCAGTTCCATCGGGAAGGAGATCAGCACTAAGATGGTGGGGTCAGACCAGCGCCAG AGCATCACCAGCTCCTACAAGTACCCAGAAGGATCCCCTGAGGAGAGAGCTGTCTTCATG AAGGCTTCTCGGAAAATGCTGGGCCCCCAAAGAGCTTCTTTGCCCTTCCTGGATCTCCTG GAGTCTGGGGGTCTTAGGGATCAGCCAGCGCAGCTGCAGCTTCACCTGGCCAGGATACCC GAGTGGGGCCAGGACCTGCAGCTGCTGCTGCGTATCCAGAGGGTGCCAGACAGCACCCAC CCTCGGGGGCCCATCGGACTGGTGGTGCGCTTCTGTGCACAGGCCCTGCTGCATGGGGGT GGTACCCAGAAGCCCTTCTGGAGGCACACAGTGCGGATGAACCTGGACTTTGGGAAGGAG ACACAGTGGCCGCTCCTCCTGCCCTACAGCAATTACAGAAACAAGCTAACGGACGAAAAG CTCATCCGCGTGTCTGGCATCGCGGAGGTTGAAGAGACAGGGAGGTCCATGCTGGTCCTA AAAGATATCTGTCTGGAGCCTCCCCACTTGTCTATTGAGGTGTCTGAGAGGGCTGAGGTG GGCAAGGCGCTGAGAGTCCATGTCACCCTCACCAACACCTTAATGGTGGCTCTGAGCAGC TGCACGATGGTGCTGGAAGGAAGCGGCCTCATCAATGGGCAGATAGCAAAGGACCTTGGG ACTCTGGTGGCCGGACACACCCTCCAAATTCAACTGGACCTCTACCCGACCAAAGCTGGA CCCCGCCAGCTCCAGGTTCTCATCAGCAGCAACGAGGTCAAGGAGATCAAAGGCTACAAG GACATCTTCGTCACTGTGGCTGGGGCTCCCTGA
- Chromosome Location
- 15
- Locus
- 15q15.2
- External Identifiers
Resource Link UniProtKB ID Q96PF1 UniProtKB Entry Name TGM7_HUMAN GenBank Protein ID 15425755 GenBank Gene ID AF363393 GenAtlas ID TGM7 HGNC ID HGNC:30790 - General References
- Grenard P, Bates MK, Aeschlimann D: Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z. J Biol Chem. 2001 Aug 31;276(35):33066-78. Epub 2001 Jun 4. [Article]