Dipeptidase 3

Details

Name

Dipeptidase 3

Synonyms

• 3.4.13.19

Gene Name

DPEP3

Organism

Humans

Amino acid sequence

>lcl|BSEQ0052595|Dipeptidase 3
MQPTGREGSRALSRRYLRRLLLLLLLLLLRQPVTRAETTPGAPRALSTLGSPSLFTTPGV
PSALTTPGLTTPGTPKTLDLRGRAQALMRSFPLVDGHNDLPQVLRQRYKNVLQDVNLRNF
SHGQTSLDRLRDGLVGAQFWSASVSCQSQDQTAVRLALEQIDLIHRMCASYSELELVTSA
EGLNSSQKLACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLTFTCSTPWAESSTKFRHHM
YTNVSGLTSFGEKVVEELNRLGMMIDLSYASDTLIRRVLEVSQAPVIFSHSAARAVCDNL
LNVPDDILQLLKKNGGIVMVTLSMGVLQCNLLANVSTVADHFDHIRAVIGSEFIGIGGNY
DGTGRFPQGLEDVSTYPVLIEELLSRSWSEEELQGVLRGNLLRVFRQVEKVREESRAQSP
VEAEFPYGQLSTSCHSHLVPQNGHQATHLEVTKQPTNRVPWRSSNASPYLVPGLVAAATI
PTFTQWLC

Number of residues

488

Molecular Weight

53686.865

Theoretical pI

Not Available

GO Classification

Functions

dipeptidase activity / metal ion binding / metallodipeptidase activity

Components

acrosomal vesicle / anchored component of membrane / plasma membrane

General Function

Dipeptidase that hydrolyzes cystinyl-bis-glycine. Does not hydrolyze leukotriene D4 (LTD4) into leukotriene E4 (LTE4).

Specific Function

Dipeptidase activity

Pfam Domain Function

• Peptidase_M19 (PF01244)

Transmembrane Regions

Not Available

Cellular Location

Membrane

Gene sequence

>lcl|BSEQ0052596|Dipeptidase 3 (DPEP3)
ATGCAGCCCACGGGCCGCGAGGGTTCCCGCGCGCTCAGCCGGCGGTATCTGCGGCGTCTG
CTGCTCCTGCTACTGCTGCTGCTGCTGCGGCAGCCCGTAACCCGCGCGGAGACCACGCCG
GGCGCCCCCAGAGCCCTCTCCACGCTGGGCTCCCCCAGCCTCTTCACCACGCCGGGTGTC
CCCAGCGCCCTCACTACCCCAGGCCTCACTACGCCAGGCACCCCCAAAACCCTGGACCTT
CGGGGTCGCGCGCAGGCCCTGATGCGGAGTTTCCCACTCGTGGACGGCCACAATGACCTG
CCCCAGGTCCTGAGACAGCGTTACAAGAATGTGCTTCAGGATGTTAACCTGCGAAATTTC
AGCCATGGTCAGACCAGCCTGGACAGGCTTAGAGACGGCCTCGTGGGTGCCCAGTTCTGG
TCAGCCTCCGTCTCATGCCAGTCCCAGGACCAGACTGCCGTGCGCCTCGCCCTGGAGCAG
ATTGACCTCATTCACCGCATGTGTGCCTCCTACTCTGAACTCGAGCTTGTGACCTCAGCT
GAAGGTCTGAACAGCTCTCAAAAGCTGGCCTGCCTCATTGGCGTGGAGGGTGGTCACTCA
CTGGACAGCAGCCTCTCTGTGCTGCGCAGTTTCTATGTGCTGGGGGTGCGCTACCTGACA
CTTACCTTCACCTGCAGTACACCATGGGCAGAGAGTTCCACCAAGTTCAGACACCACATG
TACACCAACGTCAGCGGATTGACAAGCTTTGGTGAGAAAGTAGTAGAGGAGTTGAACCGC
CTGGGCATGATGATAGATTTGTCCTATGCATCGGACACCTTGATAAGAAGGGTCCTGGAA
GTGTCTCAGGCTCCTGTGATCTTCTCCCACTCAGCTGCCAGAGCTGTGTGTGACAATTTG
TTGAATGTTCCCGATGATATCCTGCAGCTTCTGAAGAACGGTGGCATCGTGATGGTGACA
CTGTCCATGGGGGTGCTGCAGTGCAACCTGCTTGCTAACGTGTCCACTGTGGCAGATCAC
TTTGACCACATCAGGGCAGTCATTGGATCTGAGTTCATCGGGATTGGTGGAAATTATGAC
GGGACTGGCCGGTTCCCTCAGGGGCTGGAGGATGTGTCCACATACCCAGTCCTGATAGAG
GAGTTGCTGAGTCGTAGCTGGAGCGAGGAAGAGCTTCAAGGTGTCCTTCGTGGAAACCTG
CTGCGGGTCTTCAGACAAGTGGAAAAGGTGAGAGAGGAGAGCAGGGCGCAGAGCCCCGTG
GAGGCTGAGTTTCCATATGGGCAACTGAGCACATCCTGCCACTCCCACCTCGTGCCTCAG
AATGGACACCAGGCTACTCATCTGGAGGTGACCAAGCAGCCAACCAATCGGGTCCCCTGG
AGGTCCTCAAATGCCTCCCCATACCTTGTTCCAGGCCTTGTGGCTGCTGCCACCATCCCA
ACCTTCACCCAGTGGCTCTGCTGA

Chromosome Location

16

Locus

16q22.1

External Identifiers

Resource	Link
UniProtKB ID	Q9H4B8
UniProtKB Entry Name	DPEP3_HUMAN
HGNC ID	HGNC:23029

General References

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4. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details